vet-202202-0006 ArticleInAPeriodical 2022 Veterinární medicína 67 2 105-111 KimJ KimD SeoD HwangH KimY ChungT LimS LeeH KimM ParkS YounH Clinical application of both amniotic membranes and adipose derived mesenchymal stem cells in a cat with a large skin defect Surgical procedures on large skin defects can be challenging in the short term due to the size of the lesion, infection, and tissue defect. A regenerative therapy for skin wounds has been applied to promote the healing process. An 8-month-old, Korean domestic short-haired female cat, weighing 3 kg, was rescued with extensive defects on the right flank to right inguinal region caused by bite wounds. In this case, amniotic membranes and adipose-derived mesenchymal stem cells were used as the regenerative therapy to treat the large skin defect rather than a surgical intervention alone. To the best of our knowledge, this is the first report of a case with of a large skin defect treated by applying allogeneic amniotic membranes and allogeneic mesenchymal stem cells to a cat.