Vet Med - Czech, 2019, 64(7):302-308 | DOI: 10.17221/168/2018-VETMED

Association of Anti-Müllerian Hormone concentrations between the pregnancy rates and pregnancy continuity of cows in different age groupsOriginal Paper

Ahmet Sabuncu1, Gamze Evkuran Dal*,1, Sinem Ozlem Enginler1, Omur Kocak2, Ramazan Arici3
1 Department of Obstetrics and Gynaecology, Faculty of Veterinary Medicine, Istanbul University - Cerrahpasa, Istanbul, Turkey
2 Department of Animal Breeding and Husbandy, Faculty of Veterinary Medicine, Istanbul University - Cerrahpasa, Istanbul, Turkey
3 Department of Reproduction and Artificial Insemination, Faculty of Veterinary Medicine, Istanbul University - Cerrahpasa, Istanbul, Turkey

The potential relationships between Anti-Müllerian Hormone (AMH) concentrations and fertility were investigated by examining pregnancy rates and early pregnancy loss in different age groups of cows. Holstein heifers (17.35 ± 1.35 months, n = 20), young cows (3.25 ± 1.02 years, n = 20), and old cows (6.7 ± 0.80 years, n = 20) were synchronised and time fixed inseminated. A single blood sample per animal was taken during oestrus just before artificial insemination (AI), (Day 0) for the AMH analysis. The highest plasma AMH concentrations were determined in the heifer group (149.01 ± 12.62 pg/ml, P < 0.001) in the study. The AMH concentrations and conception rates decreased with age. The Day-0-AMH concentrations were higher in the pregnant animals at Day 20 after AI than in the non-pregnant animals (P < 0.05) in each group. The mean Day-0-AMH concentrations in the pregnant animals at Day 60 after AI was higher (P < 0.001) than the AMH concentrations in those with a detected pregnancy loss between D20 and D60, and also in those with a pregnancy loss and not being pregnant by Day 20 considered together. When each group was assessed on its own, based on the pregnancy results of Day 60, the Day-0-AMH concentrations were found to be significantly higher in the pregnant heifers than in the non-pregnant heifers and heifers with a pregnancy loss (P < 0.05). In conclusion, the AMH analysis might provide valuable information on the reproductive efficiency of the animals in a herd.

Keywords: bovine livestock management; herd management

Published: July 31, 2019  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Sabuncu A, Evkuran Dal G, Enginler SO, Kocak O, Arici R. Association of Anti-Müllerian Hormone concentrations between the pregnancy rates and pregnancy continuity of cows in different age groups. Vet Med - Czech. 2019;64(7):302-308. doi: 10.17221/168/2018-VETMED.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Arouche N, Picard JY, Monniaux D, Jamin SP, Vigier B, Josso N, Cate RL, di Clemente N, Taieb J (2015): The BOC ELISA, a ruminant-specific AMH immunoassay, improves the determination of plasma AMH concentration and its correlation with embryo production in cattle. Theriogenology 84, 1397-1404. Go to original source... Go to PubMed...
    2. Ball BA, Conley AJ, MacLaughlin DT, Grundy SA, Sabuer K, Liu IKM (2008): Expression of anti-Müllerian hormone (AMH) in equine granulosa-cell tumors and in normal equine ovaries. Theriogenology 70, 968-977. Go to original source... Go to PubMed...
    3. Baruselli PS, Batista EOS, Vieira LM, Souza AH (2015): Relationship between follicle population, AMH concentration and fertility in cattle. Animal Reproduction 12, 487-497.
    4. Jimenez-Krassel F, Scheetz DM, Neuder LM, Ireland JL, Pursley JR, Smith GW, Tempelman RJ, Ferris T, Roudebush WE, Mossa F, Lonergan P, Evans AC, Ireland JJ (2015): Concentration of anti-Müllerian hormone in dairy heifers is positively associated with productive herd life. Journal of Dairy Science 98, 3036-3045. Go to original source... Go to PubMed...
    5. Kumar A, Kalra B, Patel A, McDavid L, Roudebush WE (2010): Development of a second generation anti-Müllerian hormone (AMH) ELISA. Journal of Immunological Methods 362, 51-59. Go to original source... Go to PubMed...
    6. La Marca A, Volpe A (2006): Anti-Müllerian hormone (AMH) in female reproduction: is measurement of circulating AMH a useful tool? Clinical Endocrinology 64, 603-610. Go to original source... Go to PubMed...
    7. Mossa F, Walsh SW, Butler ST, Berry DP, Carter F, Lonergan P, Smith GW, Ireland JJ, Evans AC (2012): Low numbers of ovarian follicles ≥ 3 mm in diameter are associated with low fertility in dairy cows. Journal of Dairy Science 95, 2355-2361. Go to original source... Go to PubMed...
    8. Pfeiffer KE, Jury LJ, Larson JE (2014): Determination of anti-Müllerian hormone at estrus during a synchronized and a natural bovine estrous cycle. Domestic Animal Endocrinology 46, 58-64. Go to original source... Go to PubMed...
    9. Riberio ES, Bisinotto RS, Lima FS, Greco LF, Morrison A, Kumar A, Thatcher WW (2014): Plasma anti-Müllerian hormone in adult dairy cows and associations with fertility. Journal of Dairy Science 97, 6888-6900. Go to original source... Go to PubMed...
    10. Rico C, Fabre S, Medigue C, di Clemente N, Clement F, Bontoux M, Touze JL, Dupont M, Briant E, Remy B, Beckers JF, Monniaux D (2009): Anti-Müllerian hormone is an endocrine marker of ovarian gonadotropin-responsive follicles and can help to predict superovulatory responses in the cow. Biology of Reproduction 80, 50-59. Go to original source... Go to PubMed...
    11. Roelofs J, Lopez-Gatius F, Hunter RH, van Eerdenburg FJCM, Hanzen C (2010): When is a cow in estrus? Clinical and practical aspects. Theriogenology 74, 327-344. Go to original source... Go to PubMed...
    12. Rota A, Ballarin C, Vigier B, Cozzi B, Rey R (2002): Age dependent changes in plasma anti-Müllerian hormone concentrations in bovine male, female, and freemartin from birth to puberty: relationship between testosterone production and influence on sex differentiation. General and Comparative Endocrinology 129, 39-44. Go to original source... Go to PubMed...
    13. Tanaka M, Kitahara G, Uematsu M, Kobayashi I, Hemmi K, Osawa T (2018): Association of antral follicle count and peripheral anti-Müllerian hormone concentrations with fertility in beef cows. Animal Reproduction 15 (Suppl. 1), 1041-1041.
    14. Vernunft A, Schwerhoff M, Viergutz T, Diederich M, Kuwer A (2015): Anti-Muellerian hormone levels in plasma of Holstein-Friesian heifers as a predictive parameter for ovum pick-up and embryo production outcomes. Journal of Reproduction and Development 61, 74-79. Go to original source... Go to PubMed...

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY NC 4.0), which permits non-comercial use, distribution, and reproduction in any medium, provided the original publication is properly cited. No use, distribution or reproduction is permitted which does not comply with these terms.


    Return to the content