Veterinární medicína, 2024 (vol. 69), issue 10
N-acetyl-β-D-glucosaminidase in clinically healthy German Shepherd dogs and dogs with early stages of chronic kidney diseaseOriginal Paper
N Marecakova, J Kacirova, C Tothova, A Madari, M Madar, M Kuricova, S Hornak
Vet Med - Czech, 2024, 69(10):337-344 | DOI: 10.17221/34/2024-VETMED 
Urinary N-acetyl-β-d-glucosaminidase (NAG) activity is associated with kidney disease. In our study, we focused on evaluating the ratio of NAG to the urinary creatinine concentration (NAG/Cr) in the German Shepherd breed. Sixty-two healthy dogs and thirteen dogs with chronic kidney disease (CKD) were examined. The healthy dogs were divided into groups based on their sex and age (puppies and adolescent dogs under 2 years, adult dogs from 2 to 6 years and seniors over 6 years), while the dogs with CKD were divided based on the disease stage (CKD stage 1 and 2). No significant difference was detected between the males and females. Regarding...
Evaluation of coagulation by thromboelastography and a velocity curve in dogs with parvoviral enteritisOriginal Paper
O Eralp Inan, P Levent, A Saril, L Hamabe, M Kocaturk, Z Yilmaz
Vet Med - Czech, 2024, 69(10):345-354 | DOI: 10.17221/49/2024-VETMED
Canine parvoviral enteritis (CPE) has a high mortality rate in untreated dogs due to systemic inflammation and multi-organ dysfunction. The inflammatory process can lead to coagulation abnormalities. This study aimed to evaluate the coagulation status using thromboelastography (TEG) and assess the thrombin generation (TG) and clot dissolution using TEG-derived velocity curve (v-curve) parameters in dogs with CPE. It included 21 dogs with CPE and five healthy dogs. In addition to the clinico-haemato-biochemical examinations, the coagulation status was analysed using citrated venous blood samples with TEG. All the dogs with CPE met at least two criteria...
Evaluation of CTX-I, CTX-II, TIMP-I, MMP-9 and PIICP in the population of working German Shepherd dogs in SlovakiaShort Communication
S Maresova, T Liptak, A Madari, P Zeleznik, C Tothova, M Kuricova
Vet Med - Czech, 2024, 69(10):355-361 | DOI: 10.17221/127/2023-VETMED
The aim of this study was to determine the reference values of cartilage damage biomarkers in the blood and urine in 76 clinically healthy German Shepherd dogs. We grouped the dogs into 4 groups by age. All the groups were consistently made up of 19 dogs. The mean age and average body weight were established for all the dog groups. The blood was collected from the vena cephalica antebrachii or the vena saphena medialis and the urine sample was taken by us-guided cystocenthesis. The biomarkers were determined using quantitative sandwich ELISA kits. The mean values of the biomarkers ± SD were, for the urine biomarkers, CTX-I 3.29 ±...
An unusual finding of schwannoma in the mammary gland of a dogCase Report
M Makovicka, P Bolgac, K Kajo, P Makovicky, P Svorc
Vet Med - Czech, 2024, 69(10):362-368 | DOI: 10.17221/41/2024-VETMED
Peripheral nerve sheath tumours (PNSTs) are rare in the mammary glands of dogs. Here, we report a case of a schwannoma, composed of two parts, of the mammary gland of a dog. The first part consists of clusters of uncircumscribed, alternating, more concentrated and looser regions. In the more concentrated parts, typical fascicularly arranged schwannoma intermingle in plexiform arrangement, more subtle in appearance than in neuronal tumour areas. The second part undergoes regression consisting predominantly of residual shorter rosettes of cells with the presence of a peculiar variably sized swirling of target-like formations consisting of compact, thicker,...