Vet Med - Czech, 2019, 64(7):309-316 | DOI: 10.17221/19/2019-VETMED
Platelet-rich plasma, bone marrow and chitosan in minimally invasive plate osteosynthesis of canine tibia fractures - a randomized studyOriginal Paper
- 1 Veterinary Hospital Adílio Santos de Azevedo, Federal Institute of Education, Science and Technology of Paraíba, Sousa, Paraiba, Brazil
- 2 Department of Veterinary Clinic and Surgery, School of Agricultural and Veterinary Sciences of the Universidade Estadual Paulista, Jaboticabal, São Paulo, Brazil
- 3 Institute of Science and Technology, Federal University of Alfenas, Campus Poços de Caldas, Alfenas, Minas Gerais, Brazil
The goal of this study was to analyse the effects of percutaneous application of platelet rich plasma (PRP), autologous bone marrow concentrate (BM) and chitosan gel (CHI) on bone consolidation following minimally invasive plate osteosynthesis (MIPO) of the fractures of the tibia in dogs. Client-owned dogs (n = 30) with tibial fracture were divided into four treatment groups - Group 1 (control), Group 2 (BM), Group 3 (PRP) and Group 4 (CHI). The biomaterial specific to each group was injected at the fracture site immediately after the MIPO procedure. Serial radiographs were used to determine the fracture line and the development of periosteal callus immediately after surgery and at 15, 30, 60, 90 and 120 days post-surgery. There was no significant difference (P > 0.05) in the degree of oedema or grade of lameness between the groups. Grade 4 (minimum) or 5 lameness (absent) was observed in 70% of animals from all groups at 15 days post-surgery. The biomaterials PRP, BM and CHI combined with MIPO contribute to bone consolidation of tibial fractures in dogs and do not cause adverse reactions or fracture complications. Bone marrow concentrate results in shorter bone consolidation time.
Keywords: bone consolidation; surgery; biomaterials; dogs; percutaneous application
Published: July 31, 2019 Show citation
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