Vet Med - Czech, 2020, 65(10):457-463 | DOI: 10.17221/87/2020-VETMED
Imaging findings of renal telangiectasia in a Maltese dogCase Report
- 1 Department of Veterinary Diagnostic Imaging, College of Veterinary Medicine, Kyungpook National University, Daegu, Republic of Korea
- 2 Department of Veterinary Clinical Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu, Republic of Korea
- 3 Jung Animal Clinic, Daegu, Republic of Korea
A 13-year-old neutered male Maltese dog presented with a three-month history of haematuria. The abdominal ultrasound and computed tomography revealed a large, multifocally-calcified left renal mass that was disrupting most of the renal parenchyma. Most of the areas of this mass did not show any contrast enhancement on the CT. After a nephrectomy, renal telangiectasia was diagnosed on the histopathology. Renal telangiectasia is a hereditary dysplastic blood vessel disease only previously reported in Pembroke Welsh Corgi. This is the first diagnostic imaging report of renal telangiectasia and the first report in a Maltese. Renal telangiectasia should be considered for the differential diagnosis of destructive renal masses with faint or no contrast enhancement on a CT, even in cases of unilateral renal involvement in Maltese dogs or those in non-corgi breeds.
Keywords: canine; computed tomography; non-corgi breed; renal mass
Received: April 11, 2020; Accepted: August 26, 2020; Published: October 31, 2020 Show citation
References
- Ardelean DS, Letarte M. Anti-angiogenic therapeutic strategies in hereditary hemorrhagic telangiectasia. Front Genet. 2015 Feb 11;6:35.
Go to original source...
Go to PubMed...
- Bryan JN, Henry CJ, Turnquist SE, Tyler JW, Liptak JM, Rizzo SA, Sfiligoi G, Steinberg SJ, Smith AN, Jackson T. Primary renal neoplasia of dogs. J Vet Intern Med. 2006 Sep-Oct;20(5):1155-60.
Go to original source...
- Cnossen WR, Drenth JP. Polycystic liver disease: An overview of pathogenesis, clinical manifestations and management. Orphanet J Rare Dis. 2014 May 1;9:1-13.
Go to original source...
Go to PubMed...
- Diters RW, Wells M. Renal interstitial cell tumors in the dog. Vet Pathol. 1986 Jan;23(1):74-6.
Go to original source...
Go to PubMed...
- Gajanayake I, Priestnall SL, Benigni L, English K, Summers BA, Garden OA. Paraneoplastic hypercalcemia in a dog with benign renal angiomyxoma. J Vet Diagn Invest. 2010 Sep;22(5):775-80.
Go to original source...
Go to PubMed...
- Herman S. Computed tomography contrast enhancement principles and the use of high-concentration contrast media. J Comput Assist Tomogr. 2004 Jul-Aug;28:S7-11.
Go to original source...
Go to PubMed...
- Jain RK, Kozak KR. Molecular pathophysiology of tumors. In: Halperin EC, Parez CA, Brady LW, editors. Principles and practice of radiation encology. Philadelphia, USA: Lippincott Williams & Wilkins; 2008. p. 126-41.
- Katabathina VS, Vikram R, Nagar AM, Tamboli P, Menias CO, Prasad SR. Mesenchymal neoplasms of the kidney in adults: Imaging spectrum with radiologic-pathologic correlation. Radiographics. 2010 Oct;30(6):1525-40.
Go to original source...
Go to PubMed...
- Konde LJ, Wrigley RH, Park RD, Lebel JL. Sonographic appearance of renal neoplasia in the dog. Vet Radiol. 1985 May;26(3):74-81.
Go to original source...
- Moore FM, Thorton GW. Telangiectasia of Pembroke welsh corgi dogs. Vet Pathol. 1983 Mar;20(2):203-8.
Go to original source...
Go to PubMed...
- Na X, Wu G, Ryan CK, Schoen SR, di'Santagnese PA, Messing EM. Overproduction of vascular endothelial growth factor related to von Hippel-Lindau tumor suppressor gene mutations and hypoxia-inducible factor-1 alpha expression in renal cell carcinomas. J Urol. 2003 Aug; 170:588-92.
Go to original source...
Go to PubMed...
- Nyland TG, Widmer WR, Mattoon JS. Urinary tract. In: Mattoon JS. Nyland TG, editors. Small animal diagnostic ultrasound. St. Louis, USA: Elsevier Health Sciences; 2002. p. 557-607.
Go to original source...
- Park HA, Jeong CW, Kim GS, Kim HJ, Do SH, Park HM. Primary renal fibrosarcoma with local invasion into the mesenteric membrane of a mongrel dog. Korean J Vet Res. 2015 Mar;55(1):65-9.
Go to original source...
- Sadick H, Naim R, Gossler U, Hormann K, Riedel F. Angiogenesis in hereditary hemorrhagic telangiectasia: VEGF165 plasma concentration in correlation to the VEGF expression and microvessel density. Int J Mol Med. 2005 Jan; 15(1):15-9.
Go to original source...
- Seiler GS. Kidneys and ureters. In: Thrall DE, editor. Textbook of veterinary diagnostic radiology. St. Louis, US: Elsevier Health Sciences; 2018. p. 823-45.
Go to original source...
- Sheth S, Scatarige JC, Horton KM, Corl FM, Fishman EK. Current concepts in the diagnosis and management of renal cell carcinoma: Role of multidetector CT and threedimensional CT. Radiographics.2001 Oct;21:S237-54.
Go to original source...
Go to PubMed...
- Weyman PJ, McClennan BL, Lee JK, Stanley RJ. CT of calcified renal masses. AJR Am J Roentgenol. 1982 Jun;138 (6):1095-9.
Go to original source...
Go to PubMed...
- Zini E, Bovero A, Nigrisoli E, Ratto A, Rampazzo A, Zatelli A. Sarcomatoid renal cell carcinoma with osteogenic differentiation and paraneoplastic hepatopathy in a dog, possibly related to human Stauffer's syndrome. J Comp Pathol. 2003 Nov;129(4):303-7.
Go to original source...
Go to PubMed...
This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY NC 4.0), which permits non-comercial use, distribution, and reproduction in any medium, provided the original publication is properly cited. No use, distribution or reproduction is permitted which does not comply with these terms.