Vet Med - Czech, 2015, 60(11):629-634 | DOI: 10.17221/8531-VETMED

Effects of dietary gamma-aminobutyric acid on egg production, egg quality, and blood profiles in layer hensOriginal Paper

J.H. Park, I.H. Kim
Department of Animal Resource and Science, Dankook University, Cheonan, Republic of Korea

Hy-line brown commercial layers (32 weeks old) were used to investigate the effects of GABA (gamma-aminobutyric acid) derived from E. coli strains on productivity, egg quality, and blood profile. In total, 288 birds (1946 ± 0.5 g) were fed four different levels of GABA (0, 25, 50, and 100 ppm), in a basal diet based on corn-soybean meal, for five weeks. Egg production, egg weight, and egg mass during weeks 32 to 36 showed significant improvement, as dietary GABA was increased from 0 to 100 ppm (linear, P < 0.05). Additionally, GABA supplementation was associated with increased eggshell breaking strength and albumen height (quadratic and linear, P < 0.05). Blood variables, such as white blood cells, red blood cells, lymphocyte, cortisol, epinephrine, and norepinephrine concentrations, were not influenced by addition of GABA to the diet; however, the haptoglobin concentration decreased significantly (linearly) and the IgG concentration increased (quadratically) in the GABA-fed groups (P < 0.05). These results suggest that diets containing GABA may beneficially affect productivity, egg quality, serum haptoglobin, and IgG concentrations in layers.

Keywords: gamma-aminobutyric acid; egg production; egg quality; blood profile; layer

Published: November 30, 2015  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Park JH, Kim IH. Effects of dietary gamma-aminobutyric acid on egg production, egg quality, and blood profiles in layer hens. Vet Med - Czech. 2015;60(11):629-634. doi: 10.17221/8531-VETMED.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Adeghate E, Ponery AS (2002): GABA in the endocrine pancreas: cellular localization and function in normal and diabetic rats. Tissue and Cell 34, 1-6. Go to original source... Go to PubMed...
    2. Chen Z, Tang J, Sun YQ, Xie J (2013): Protective effect of γ-aminobutyric acid on antioxidation function in intestinal mucosa of Wenchang chicken induced by heat stress. Journal of Animal and Plant Sciences 23, 1634-1641.
    3. Chung HJ, Jang SH, Cho HY, Lim ST (2009): Effects of steeping and anaerobic treatment on GABA (gamma;-aminobutyric acid) content in germination waxy hull-less barely. LWTFood Science and Technology 42, 1712-1716. Go to original source...
    4. Dai SF, Gao F, Zhang WH, Song SX, Xu XL, Zhou GH (2011): Effects of dietary glutamine and gamma-aminobutyric acid on performance, carcass characteristics and serum parameters in broilers under circular heat stress. Animal Feed Science and Technology 168, 51-60. Go to original source...
    5. Fan ZY, Deng JP, Liu GH, Cai HY, He JH, Wu MX, Zheng FY (2007): Effects of γ-aminobutyric acid on the performance and internal hormone levels in growing pigs. Chinese Journal of Animal Nutrition 19, 350-356.
    6. Hay M, Mormède P (1997): Determination of catecholamines and methoxycatecholamines excretion patterns in pig and rat urine by ion-exchange liquid chromatography with electrochemical detection. Journal of Chromatography B 703, 15-23. Go to original source... Go to PubMed...
    7. Huang HL, Zhao WJ, Zou XT, Li H, Zhang M, Dong XY. (2011): Effect of γ-aminobutyric acid on incubation, immunity and antioxidation activity in pigeon. Chinese Journal of Veterinary Science 9, 1327-1331.
    8. Jin Z, Mendu SK, Birnir B (2013): GABA is an effective immunomodulatory molecule. Amino Acids 45, 87-94. Go to original source... Go to PubMed...
    9. Kimura M, Hayakawa K, Sansawa H (2002): Involvement of γ-aminobutyric acid (GABA) B receptors in the hypotensive effect of systemically administered GABA in spontaneously hypertensive rats. Japanese Journal of Pharmacology 89, 388-394. Go to original source... Go to PubMed...
    10. Koutsos EA, Lopez JGC, Klasing KC (2006): Carotenoids from in ovo or dietary sources blunt systemic indices of the inflammatory response in growing chicks (Gallus gallus domesticus). Journal of Nutrition 136, 1027- 1031. Go to original source... Go to PubMed...
    11. Liang Z, Fan ZY, Chen YH, Zhou DG, Wu XS, He JH, Zhu LT, Fu CX, Peng HZ, Luo R (2009): Effects of different levels of γ-aminobutyric acid on the performance and serum hormone levels of lactating sows. Chinese Journal of Animal Nutrition 21, 592-597.
    12. Lu X, Xie C, Gu Z (2008): Isolation of γ-aminobutyric acid producing bacteria and optimization of fermentative medium. Biochemical Engineering Journal 41, 48-52. Go to original source...
    13. McCorry LK (2007): Physiology of the autonomic nervous system. American Journal of Pharmaceutical Education 71, article 78. Go to original source... Go to PubMed...
    14. Oh SH, Choi WG (2000): Production of the quality germinated brown rices containing high γ-aminobutyric acid by chitosan application. Korean Journal of Biotechnology and Bioengineering 15, 615-620.
    15. Omori M, Yano T, Okamoto J, Tsushida T, Murai T, Higuchi M (1987): Effect of anaerobically treated tea (gabaron tea) on blood pressure of spontaneously hypertensive rats. Nippon Nogeikagaku Kaishi 61, 1449-1551. Go to original source...
    16. Rosmond R, Bouchard C, Bjorntorp P (2002): Allelic variants in the GABAA a6 receptor subunit gene (GABRA6) is associated with abdominal obesity and cortisol secretion. International Journal of Obesity 26, 938-941. Go to original source... Go to PubMed...
    17. Smith DK, Kassam T, Singh B, Elliott JF (1992): Escherichia coli has two homologous glutamate decarboxylase genes that map to distinct loci. Journal of Bacteriology 174, 5820-5826. Go to original source... Go to PubMed...
    18. Wang DM, Wang C, Liu HY, Liu JX, Ferguson JD (2013): Effect of rumen protected γ-aminobutyric acid on performance and health status of early lactating dairy cows. Journal of Dairy Science 96, 3222-3227. Go to original source... Go to PubMed...
    19. Xie WY, Hou XY, Yan FB, Sun GR, Han RL, Kang XT (2013): Effect of γ-aminobutyric acid on growth performance and immune function in chicks under beak trimming stress. Animal Science Journal 84, 121-129. Go to original source... Go to PubMed...
    20. Yang XJ, Pan CL, Zhu YM, Huang YL, Zhang YS, Li AX, Chen WH, Zou SX (2009): Effects of γ-aminobutyric acid on growth performance and hormone levels in serum of weanling piglets. Chinese Journal of Animal Nutrition 21, 388-392.
    21. Zhang M, Zou XT, Li H, Dong XY, Zhao W (2012): Effect of dietary γ-aminobutyric acid on laying performance, egg quality, immune activity and endocrine hormone in heat-stressed Roman hens. Animal Science Journal 83, 141-147. Go to original source... Go to PubMed...
    22. Zhu YZ, Cheng JL, Ren M, Yin L, Piao XS (2015): Effect of γ-aminobutyric acid-producing Lactobacillus strain on laying performance, egg quality and serum enzyme activity in Hy-Line brown hens under heat stress. Asian Australasian Journal of Animal Sciences 28, 1006-1013. Go to original source... Go to PubMed...

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY NC 4.0), which permits non-comercial use, distribution, and reproduction in any medium, provided the original publication is properly cited. No use, distribution or reproduction is permitted which does not comply with these terms.


    Return to the content