Vet Med - Czech, 2024, 69(5):177-183 | DOI: 10.17221/2/2024-VETMED

Feline gastrointestinal eosinophilic sclerosing fibroplasia in two cats: Serial ultrasonographic and computed tomography findingsCase Report

D Noh ORCID...1, H Jo2, H Shin3, SW Lee ORCID...2, S Choi ORCID...4, K Lee ORCID...2
1 Department of Veterinary Medical Imaging, College of Veterinary Medicine, Kyungpook National University, Daegu, Republic of Korea
2 24 Africa Animal Medical Center, Daejeon, Republic of Korea
3 College of Veterinary Medicine, Kangwon National University, Chuncheon, Republic of Korea

A 6-month-old Ragdoll and 9-year-old Russian Blue cat presented with vomiting. Ultrasonography and computed tomography showed a pyloric antrum mass with wall layering loss and regional lymphadenopathy in the Ragdoll kitten. The Russian Blue cat only presented with muscularis layer thickening throughout the jejunum; however, despite medications, it later progressed to a mass with wall layering loss on the serial ultrasound. Both cats underwent surgery, and feline gastrointestinal eosinophilic sclerosing fibroplasia (FGESF) was histologically confirmed. FGESF should be considered for gastrointestinal masses demonstrating wall layering loss and lymphadenopathy, even in kittens, and intestinal muscularis layer thickening that is refractory to medications.

Keywords: diagnostic imaging; FGESF; gastrointestinal tumor; inflammatory bowel disease

Received: January 15, 2024; Revised: April 12, 2024; Accepted: April 17, 2024; Published: May 27, 2024  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Noh D, Jo H, Shin H, Lee S, Choi S, Lee K. Feline gastrointestinal eosinophilic sclerosing fibroplasia in two cats: Serial ultrasonographic and computed tomography findings. Vet Med - Czech. 2024;69(5):177-183. doi: 10.17221/2/2024-VETMED.
Download citation

References

  1. Cerna P, Lopez-Jimenez C, Fukushima K, Nakashima K, Nakagawa T, Adam F, Groth A, Denning A, Israeliantz N, Gunn-Mooreet DA. Clinicopathological findings, treatment, and outcome in 60 cats with gastrointestinal eosinophilic sclerosing fibroplasia. J Vet Intern Med. 2024 Mar-Apr;38(2):1005-12. Go to original source... Go to PubMed...
  2. Craig LE, Hardam EE, Hertzke DM, Flatland B, Rohrbach BW, Moore RR. Feline gastrointestinal eosinophilic sclerosing fibroplasia. Vet Pathol. 2009 Jan;46(1):63-70. Go to original source... Go to PubMed...
  3. Goffart LM, Durand A, Dettwiler M, Vincenti S. Feline gastrointestinal eosinophilic sclerosing fibroplasia presenting as a rectal mass. JFMS Open Rep. 2022 Aug 10;8(2):20551169221114330. Go to original source... Go to PubMed...
  4. Grau-Roma L, Galindo-Cardiel I, Isidoro-Ayza M, Fernandez M, Majo N. A case of feline gastrointestinal eosinophilic sclerosing fibroplasia associated with phycomycetes. J Comp Pathol. 2014 Nov;151(4):318-21. Go to original source... Go to PubMed...
  5. Kaji N, Hori M. Interstitial cells of Cajal in gastrointestinal inflammatory diseases. J Smooth Muscle Res. 2023;59:1-13. Go to original source... Go to PubMed...
  6. Lawrance IC, Maxwell L, Doe W. Inflammation location, but not type, determines the increase in TGF-beta1 and IGF-1 expression and collagen deposition in IBD intestine. Inflamm Bowel Dis. 2001 Feb;7(1):16-26. Go to original source... Go to PubMed...
  7. Linton M, Nimmo JS, Norris JM, Churcher R, Haynes S, Zoltowska A, Hughes S, Lessels NS, Wright M, Malik R. Feline gastrointestinal eosinophilic sclerosing fibroplasia: 13 cases and review of an emerging clinical entity. J Feline Med Surg. 2015 May;17(5):392-404. Go to original source... Go to PubMed...
  8. Martineau M, Tilmant C, Risco Castillo V, Guillot J, Reyes-Gomez E, Benchekroun G, Freiche V. A case of feline gastrointestinal eosinophilic sclerosing fibroplasia associated with fungal colonisation: Endoscopic features, treatment and follow-up. JFMS Open Rep. 2023 May 9;9(1):20551169231165246. Go to original source... Go to PubMed...
  9. Oliveira SH, Taub DD, Nagel J, Smith R, Hogaboam CM, Berlin A, Lukacs NW. Stem cell factor induces eosinophil activation and degranulation: Mediator release and gene array analysis. Blood. 2002 Dec 15;100(13):4291-7. Go to original source... Go to PubMed...
  10. Penninck DG, Moore AS, Tidwell AS, Matz ME, Freden GO. Ultrasonography of alimentary lymphosarcoma in the cat. Vet Radiol Ultrasound. 1994 Jul;35(4):299-304. Go to original source...
  11. Porras N, Rebollada-Merino A, Rodriguez-Franco F, Calvo-Ibbitson A, Rodriguez-Bertos A. Feline gastrointestinal eosinophilic sclerosing fibroplasia-extracellular matrix proteins and TGF-β1 immunoexpression. Vet Sci. 2022 Jun 13;9(6):291. Go to original source... Go to PubMed...
  12. Simeoni F, Signore FD, Terragni R, Tamburro R, Aste G, Vignoli M. Diagnostic imaging of gastrointestinal tumours in dogs and cats: A review. Am J Anim Vet Sci. 2020 Apr;15(2):89-101. Go to original source...
  13. Tai Y, Woods EL, Dally J, Kong D, Steadman R, Moseley R, Midgley AC. Myofibroblasts: Function, formation, and scope of molecular therapies for skin fibrosis. Biomolecules. 2021 Jul 23;11(8):1095. Go to original source... Go to PubMed...
  14. Tanaka T, Noguchi S, Wada Y, Nishida H, Akiyoshi H. Preliminary study of CT features of intermediate- and high-grade alimentary lymphoma and adenocarcinoma in cats. J Feline Med Surg. 2022 Oct;24(10):1065-71. Go to original source... Go to PubMed...
  15. Thieme ME, Olsen AM, Woolcock AD, Miller MA, Simons MC. Diagnosis and management of a case of retroperitoneal eosinophilic sclerosing fibroplasia in a cat. JFMS Open Rep. 2019 Aug 16;5(2):2055116919867178. Go to original source... Go to PubMed...
  16. Weissman A, Penninck D, Webster C, Hecht S, Keating J, Craig LE. Ultrasonographic and clinicopathological features of feline gastrointestinal eosinophilic sclerosing fibroplasia in four cats. J Feline Med Surg. 2013 Feb;15(2):148-54. Go to original source... Go to PubMed...

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY NC 4.0), which permits non-comercial use, distribution, and reproduction in any medium, provided the original publication is properly cited. No use, distribution or reproduction is permitted which does not comply with these terms.