Vet Med - Czech, 2003, 48(5):141-145 | DOI: 10.17221/5761-VETMED

Lawsonia intracellularis in a dog with inflammatory bowel disease

R. Husník, J. Klimeš, K. Tomanová, J. Smola, R. Halouzka, F. Tichý, J. Brázdil
1 , J. K 5, K. T 2, J. S 2, R. H 3, F. T 4 , J. B 6 1Small Animal Clinic, Faculty of Veterinary Medicine, 2Department of Microbiology and Immunology, Faculty of Veterinary Medicine, 3Department of Pathologic Morphology, Faculty of Veterinary Medicine, 4Department of Anatomy, Histology and Embryology, Faculty of Veterinary Medicine, 5Department of Biology and Wildlife Diseases, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic 6Institute of Pathologic Anatomy, Faculty Hospital Bohunice, Brno, Czech Republic

A two-year-old male German short-haired pointer was presented with a 1.5-year history of intermittent small-bowel diarrhoea. Inflammatory bowel disease (chronic lymphocytic-plasmacytic gastritis, enteritis and colitis) was diagnosed on the basis of histological examination of biopsies obtained on repeated endoscopy and by exclusion of other possible causes. Warthin-Starry silver staining of stomach mucosa revealed the presence of gastric spiral organisms. The evidence of L. intracellularis was provided by a positive nested polymerase chain reaction in one biopsy of duodenal mucosa and in one rectal smear. In 5 blood sera collected over a period of 8 months the IgG antibodies to L. intracellularis were found by an indirect fluorescent antibody test. Treatment with oral prednisone led only to a temporary improvement.

Keywords: Lawsonia intracellularis; dog; diarrhoea; chronic gastritis; enteritis; colitis; inflammatory bowel disease; endoscopy; nested polymerase chain reaction

Published: May 31, 2003  Show citation

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Husník R, Klimeš J, Tomanová K, Smola J, Halouzka R, Tichý F, Brázdil J. Lawsonia intracellularis in a dog with inflammatory bowel disease. Vet Med - Czech. 2003;48(5):141-145. doi: 10.17221/5761-VETMED.
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