Vet Med - Czech, 2008, 53(12):685-689 | DOI: 10.17221/1976-VETMED

Malignant peripheral nerve sheath tumour in a dog presenting as a pseudo aneurysm of the left jugular vein: a case report

M. Kostov1, Z. Mijovic2, M. Visnjic3, D. Mihailovic2, M. Stojanovic3, M. Zdravkovic2
1 Military Hospital of Nis, Serbia
2 Medical Faculty of Nis, Serbia
3 Clinic of Surgery, Clinical Center of Nis, Serbia

The authors report an autopsy case of a malignant peripheral nerve sheath tumour in a 9-year-old female Akito-ino dog, presenting as a pseudo aneurysm of the left jugular vein. Signs and symptoms included swelling of the neck and legs, dyspnea, malaise and weight loss. Post-mortem examination revealed a tumour mass (8 × 6, 5 × 6 cm), localized to the left paravertebrally, and on the level of C7 to T2 vertebral bodies; additional masses were observed in both lungs, heart and left kidney. On the basis of necropsy, histological findings and immunophenotype, the tumour was classsified as a malignant peripheral nerve sheath tumour. Immunohistochemistry especially positivity for S-100 protein can be helpful in distinguishing this type of neoplasm from other malignancies with similar morphologies.

Keywords: malignant peripheral nerve sheath tumour; dog; tumour

Published: December 31, 2008  Show citation

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Kostov M, Mijovic Z, Visnjic M, Mihailovic D, Stojanovic M, Zdravkovic M. Malignant peripheral nerve sheath tumour in a dog presenting as a pseudo aneurysm of the left jugular vein: a case report. Vet Med - Czech. 2008;53(12):685-689. doi: 10.17221/1976-VETMED.
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References

  1. Chijiwa K., Uchida K., Tateyama S. (2004): Immunohistochemical evaluation of canine peripheral nerve sheath tumors and other soft tissue sarcomas. Veterinary Pathology, 41, 307-318. Go to original source... Go to PubMed...
  2. Enzinger F.M., Weiss S.W. (1995): Malignant tumors of the peripheral nerves. In: Enzinger F.M., Weiss S.W. (eds.): Soft Tissue Tumors. Mosby-Year Book, St. Louis. 889-928.
  3. Fletcher C.D.M. (2007): Peripheral neuroectodermal tumors. In: Fletcher C.D.M. (ed.): Diagnostic Histopathology of Tumors. Churchil Livingstone Elsevier, Philadelphia. 1733-1761.
  4. Garcia P., Sanchez B., Sanchez M.A., Gonzales M., Rollan E., Flores J.M. (2004): Epithelioid malignant peripheral nerve sheath tumor in a dog. Journal of Comparative Pathology, 131, 87-91. Go to original source... Go to PubMed...
  5. Huang L., Espinoza C., Welsh R. (2003): Malignant peripheral nerve sheath tumor with diveregent differentiation. Archive of Pathology & Laboratory Medicine, 127, e147-e150. Go to original source... Go to PubMed...
  6. Miettinen M.M. (2003): Nerve sheath tumors. In: Miettinen M.M. (ed.): Diagnostic Soft Tissue Pathology. Churchill Livingstone, Philadelphia. 343-378.
  7. Okada M., Kitagawa M., Shibuya H., Kanayama K., Sato T., Yamamura H., Sakai T. (2007): Malignant peripheral nerve sheath tumor arising from the spinal canal in cat. Journal of Veterinary Medical Science, 69, 683-686. Go to original source... Go to PubMed...
  8. Patnaik A.K., Zachos T.A., Sams A.E., Aitken M.L. (2002): Malignant nerve-sheath tumor with divergent and glandular differentiation in a dog: a case report. Veterinary Pathology, 39, 406-410. Go to original source... Go to PubMed...
  9. Ramirez G.A., Herraez P., Rodriguez F., Godhino A., Andrada M., Espinosa de los Monteros A. (2007): Malignant peripheral nerve sheath tumor (malignant schwannoma) in the diaphragm of a goat. Journal of Comparative Pathology, 137, 137-141. Go to original source... Go to PubMed...
  10. Uchida K., Nakayama H., Sasaki N., Tateyama S., Goto N. (1992): Malignant schwanoma in the spinal root of a dog. Journal of Veterinary Medical Science, 54, 809-811. Go to original source... Go to PubMed...

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