Vet Med - Czech, 2012, 57(6):314-319 | DOI: 10.17221/6019-VETMED

Primary intestinal fibrosarcoma caused by intestinal perforation in a dog: a case report

H. Avci, R. Yaygingul, M. Gultekin, E.T. Epikmen, K. Ural, A. Belge, S.S. Birincioglu
Faculty of Veterinary Medicine, University of Adnan Menderes, Aydin, Turkey

An 11-year-old male Cocker Spaniel was examined for a palpable abdominal mass located in the jejunum after presenting with a history of anorexia and constipation for several weeks. In a contrast radiogram, a structure with well-defined borders adjacent to the intestine was determined. The intestinal mass, measuring 16 × 9.19 × 8.6 cm and weighing 900 g was surgically removed. At gross examination, when the lumen of a portion of the intestine excised together with the tumour mass was exposed, an ulcerated, oval-shaped area 1.2 × 0.6 cm in size was observed on the mucosa. The outer surface of the tumour was homogenous and expanded outwards from the intestinal wall. Histologically, the tumour was composed of fusiform-elongated spindle-shaped to polygonal neoplastic cells forming interlacing fascicles or interwoven bundles in an atypical herringbone pattern. Immnunohistochemically, neoplastic cells stained intensely positive for vimentin, and negative for α-SMA, desmin, cyotokeratin (AE1/AE3), S-100 protein, glial fibrillary acidic protein, neuron specific enolase and synaptophsin. On the basis of the histopathological and immunohistochemical results, the tumour was diagnosed as a fibrosarcoma. The present report is a very rare description of fibrosarcoma of the dog intestine associated with intestinal perforation.

Keywords: dog; fibrosarcoma; intestine; pathology

Published: June 30, 2012  Show citation

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Avci H, Yaygingul R, Gultekin M, Epikmen ET, Ural K, Belge A, Birincioglu SS. Primary intestinal fibrosarcoma caused by intestinal perforation in a dog: a case report. Vet Med - Czech. 2012;57(6):314-319. doi: 10.17221/6019-VETMED.
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