Vet Med - Czech, 2020, 65(1):41-47 | DOI: 10.17221/103/2019-VETMED

Transient acquired Fanconi syndrome with unusual and rare aetiologies: A case study of two dogsCase Report

JY Park¹, JH Park¹, HJ Han², JH Kim³

¹ Department of Veterinary Internal Medicine, Veterinary Medical Teaching Hospital, Konkuk University, Seoul, Republic of Korea

² Department of Veterinary Emergency, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea

³ Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea

The acquired form of Fanconi syndrome is seldom identified in dogs; those cases that have been reported have been secondary to hepatic copper toxicosis, primary hypoparathyroidism, ingestion of chicken jerky treats, exposure to ethylene glycol, or gentamicin toxicity. However, to the best of our knowledge, there have been no reports of acquired Fanconi syndrome secondary to Babesia infection or ingestion of cosmetics in dogs. We here report on two dogs presented with a history of marked polyuria, polydipsia, and lethargy. Laboratory examinations showed glucosuria with normoglycaemia and severe urinary loss of amino acids. One dog was infected with Babesia gibsoni and the other dog had a history of cosmetics ingestion. The first dog received treatment for Babesia infection and the second dog received aggressive care to correct metabolic acidosis, electrolyte imbalances, and other add-on deficiencies. In both dogs, the Fanconi syndrome was successfully managed following the treatment for the underlying causes. In conclusion, both Babesia infection and cosmetics ingestion should be considered as a possible aetiology for transient acquired Fanconi syndrome in canine patients.

Keywords: Babesiosis; cosmetics ingestion; haematological profile; enzymes; urinalysis; ultrasonography

Received: August 16, 2019; Accepted: January 5, 2020; Published: January 31, 2020  Show citation