Veterinární medicína, 2008 (vol. 53), issue 10

Morphology of small intestinal mucosa and intestinal weight change with metabolic type of cattle

R. Zitnan, J. Voigt, S. Kuhla, J. Wegner, A. Chudy, U. Schoenhusen, M. Brna, M. Zupcanova, H. Hagemeister

Vet Med - Czech, 2008, 53(10):525-532 | DOI: 10.17221/1968-VETMED  

The objective of this study was to investigate rumen fermentation, apparent digestibility of nutrients, and morphology of ruminal und intestinal mucosa in two cattle breeds of different metabolic type. From each breed six purebred German Holstein (H) bulls representing the secretion type and six Charolais (CH) bulls representing the accretion type were raised and fattened under identical conditions with semi ad libitum feeding of a high energy diet. The animals were used for a digestion trial started at nine months of age and animals were slaughtered at 18 months of age. Body weight (668 vs. 764 kg, P = 0.011), body weight gain (1 223...

Proliferative enteropathy (PPE)-induced changes in the expression of DBH, VAChT and NOS in the neurons of intramural ganglia of the porcine ileum

Z. Pidsudko, K. Wasowicz, J. Kaleczyc, M. Majewski, M. Lakomy

Vet Med - Czech, 2008, 53(10):533-542 | DOI: 10.17221/1964-VETMED  

As enteric neurons are regarded to be highly adaptive in their response to various pathological states, including inflammation, it appears to be of interest to study the chemical coding of neurons in the intramural ganglia of the ileum wall in the course of porcine proliferative enteropathy (PPE) evoked by Lawsonia intracellularis. The study was performed on 12 juvenile pigs of the Large White Polish breed. The pigs were divided into the control (C, n = 6) group and the group consisting of pigs with clinically diagnosed Lawsonia intracellularis infection (E, n = 6). In E group animals the infection was confirmed with a PCR-based...

Effects of dehydroepiandrosterone on growth performance, lipid metabolic hormones and parameters in broilers

H.T. Ma, X. Tang, C.Y. Tian, S.X. Zou, G.Q. Huang, W.H. Chen

Vet Med - Czech, 2008, 53(10):543-549 | DOI: 10.17221/1963-VETMED  

One hundred and eighty (180) day-old broiler chickens were used to investigate the effects of dehydroepiandrosterone (DHEA) on growth performance, carcass composition, and the serum concentrations of several lipid metabolic hormones and metabolic parameters (indicators). The broilers received the same basal diets, with DHEA added at 0 (control), 5 and 20 mg/kg feed. During the experimental period, broilers fed DHEA exhibited lower levels of triglycerides (TG), total serum cholesterol (TC), high density lipoprotein-cholesterol (HDL-C) and non-esterified fatty acids (NEFA) as compared to the control animals, but a marked increase in lipoprotein lipase...

Long-term application of clinoptilolite via the feed of layers and its impact on the chemical composition of long bones of pelvic limb (femur and tibiotarsus) and egg cortex

I. Herzig, E. Strakova, P. Suchy

Vet Med - Czech, 2008, 53(10):550-554 | DOI: 10.17221/1965-VETMED  

Selected 120 layers, hybrid breed Bovans Goldline, were divided into two balanced groups: control (C) and experimental (E) group. The layers were raised in three-floor cage technology with automatic watering, manual feeding, in the environment with regulated lighting and thermal schedule. The actual experimental period started in the 22nd week and ended in the 68th week of age of the layers. In the period following the filling of the cages the layers received complete feed mixture N1, subsequently, until the end of the experiment, they received feed mixture N2. The feed mixtures for Group C and E were of the same composition,...

The effect of zinc and manganese source in the diet for laying hens on eggshell and bones quality

S. Swiatkiewicz, J. Koreleski

Vet Med - Czech, 2008, 53(10):555-563 | DOI: 10.17221/1966-VETMED  

The study was conducted to evaluate the effect of zinc and manganese source (inorganic vs. organic) in the diet for hens on laying performance, eggshell quality and chosen parameters of bones. Experiment was carried out on 84 Hy Line Brown hens, from 25 to 70 weeks of age, allocated to seven experimental groups, each containing 12 hens individually caged on wire-mesh floor. All layers were fed the same basal diet contained in 1 kg 52 mg Zn and 30 mg Mn. In experimental treatments basal diet was supplemented with 30 mg Zn/kg and 50 mg Mn/kg and inorganic forms of Zn (ZnO) and Mn (MnO) were gradually replaced (in 0, 50 or 100%) with their organic sources...

Chlorambucil and fludarabine as a new pre-transplant conditioning for patients with chronic lymphocytic leukemia: results of in vivo experiments

J. Tomenendalova, J. Mayer, M. Doubek, D. Horky, K. Rehakova, J. Doubek

Vet Med - Czech, 2008, 53(10):564-571 | DOI: 10.17221/1967-VETMED  

Chronic lymphatic leukemia (CLL), incurable by standard treatments, may be potentially cured by allogeneic hematopoietic stem cell transplantation. Since CLL affects predominantly older people, there is a need for some low-toxicity conditioning with, on the other hand, strong antileukemic activity. Since there are very encouraging results with busulfan + fludarabine conditionings in myeloid malignancies and since the clinical study with the combination treatment with chlorambucil and fludarabine was stopped prematurely for myelotoxicity, we hypothesized that this chlorambucil + fludarabine combination would have the potential as a good conditioning...