Veterinární medicína, 2011 (vol. 56), issue 2
The effect of silymarin on expression of selected ABC transporters in the rat
R. Vecera, A. Zacharova, J. Orolin, N. Skottova, P. Anzenbacher
Vet Med - Czech, 2011, 56(2):59-62 | DOI: 10.17221/1579-VETMED 
Silymarin (standardized extract from the seeds of the Silybum marianum) has been used in the supportive therapy of liver diseases and its cytoprotective activity is believed to be based on antioxidant properties. Our previous works showed hypolipidemic effects of silymarin. The ATP-binding cassette (ABC) transporters G5 and G8 play a major role in biliary cholesterol secretion. The ABCA1 transporter plays a significant role in movement of cellular cholesterol to high density lipoproteins. We investigated the possibility that silymarin affects the regulation of lipid metabolism via selected ABC transporters using rats fed a high-cholesterol...
Impact of long-term supplementation of zinc and selenium on their content in blood and hair in goats
L. Pavlata, M. Chomat, A. Pechova, L. Misurova, R. Dvorak
Vet Med - Czech, 2011, 56(2):63-74 | DOI: 10.17221/1581-VETMED
This paper evaluates the impact of long-term supplementation of different forms of zinc (Zn) and selenium (Se) on the content of these substances in the blood and hair of goats. Two analogous supplementation experiments were performed. 37 goats divided into four groups were used in the first trial with the Zn supplementation. Group A (n = 10) was a control group (with no Zn administered). A further three groups (B, C, D) were supplemented with Zn in various forms. Group B (n = 9) with zinc oxide, Group C (n = 9) with zinc lactate and Group D (n = 9) with zinc chelate. The second trial with Se supplementation was...
The effect of inorganic and organically bound forms of selenium on glutathione peroxidase activity in the blood of goats
L. Pavlata, L. Misurova, A. Pechova, R. Dvorak
Vet Med - Czech, 2011, 56(2):75-81 | DOI: 10.17221/1576-VETMED
The goal of the experiment was to compare the effect of supplementation of inorganic and the new organically bound (lactate-protein selenium complex) form of selenium (Se) in feed for goats. The 31 goats were split into three groups: control (C) without Se supplementation, AN group administered sodium selenite, ORG group administered lactate-protein selenium complex (Selene Chelate, Agrobac, Czech Republic) produced by cultivation of Lactobacillus acidophilus on a substrate containing natrium selenite. The total Se intake in goats was 0.15 mg in group C, and 0.43 mg in the groups AN and ORG. The effect of Se supplementation was assessed based...
Association of Trypanosoma theileri with peritonitis in a pregnant cross-bred cow: a case report
N.K. Sood, L.D. Singla, R.S. Singh, S.K. Uppal
Vet Med - Czech, 2011, 56(2):82-84 | DOI: 10.17221/1580-VETMED
This clinical case report deals with a very rare case of the detection of Trypanosoma theileri in the peritoneal fluid of a seven-year-old eight month pregnant cross-bred cow in fourth parity showing frank peritonitis. Peritoneal tab cytology revealed chronic active peritonitis and the presence of polymorphic T. theileri organisms. The parasite was also occasionally detected in blood smears. The protozoan, considered by and large non-pathogenic, has previously been detected in aberrant body sites, other than the peritoneal cavity. A perusal of the available literature indicates that this is the first report of this large stercorarrian...
Cardiac manifestations of borreliosis in a dog: a case report
C.F. Agudelo, P. Schanilec, K. Kybicova, P. Kohout
Vet Med - Czech, 2011, 56(2):85-92 | DOI: 10.17221/1577-VETMED
In Europe Lyme disease is caused by the spirochete Borrelia burgdorferi sensu lato. It presents with a variety of clinical manifestations including heart disease and problems of the nervous system, skin and joints. Lyme carditis occurs in 4-10% of infected humans and is characterized by a plethora of cardiovascular syndromes such as arrhythmia, myocarditis, and pericarditis among others. This article is a case report of a serologically positive (B. burgdorferi s.l.) dog, in which the antibody dynamics correlated with clinical, electrocardiographic, and echocardiographic findings of heart disease resembling human Lyme-induced dilated...
Hepatopancreatic ganglioneuroma in a young dog: a case report
R. Zafra, M.J. Bautista, J. Perez, P.J. Ginel, R. Lucena
Vet Med - Czech, 2011, 56(2):93-96 | DOI: 10.17221/1578-VETMED
The clinical, pathological and immunohistochemical features of a hepatobiliary and pancreatic ganglioneuroma in a seven-month-old dog are described. The dog presented progressive weight loss, anorexia and abdominal pain. At laparoscopic examination numerous whitish nodules ranging from 0.5 to 1 cm in diameter were found in the peripancreatic tissues, the bile duct system and perihepatic tissues. Due to poor prognosis the dog was euthanized and necropsy was conducted. Tumour nodules were not noted in the other examined abdominal organs. Microscopically, the nodules were composed of large, well differentiated neurons embedded in an abundant stroma of...
Surgical removal of a ventricular foreign body from a common myna (Acridotheres tristis): a case report
F. Hayati, A. Lakzian, E. Shariati, J. Bakhtiari, N. Sayyah, M. Masoudifard, T. Vakili
Vet Med - Czech, 2011, 56(2):97-100 | DOI: 10.17221/1582-VETMED
A common myna (Acridotheres tristis) was presented to Veterinary Teaching Hospital, School of Veterinary Medicine, Tehran University after swallowing a needle. Radiography and physical examination revealed a metal foreign body within the body with its distal end in the ventriculus. Surgical removal by ventriculotomy under general anesthesia was attempted. Six months of follow up study revealed no complications.