Veterinární medicína, 2018 (vol. 63), issue 10

Epigallocatechin gallate: a reviewReview

L. Bartosikova, J. Necas

Vet Med - Czech, 2018, 63(10):443-467 | DOI: 10.17221/31/2018-VETMED  

Epigallocatechin gallate is the major component of the polyphenolic fraction of green tea and is responsible for most of the therapeutic benefits of green tea consumption. A number of preclinical in vivo and in vitro experiments as well as clinical trials have shown a wide range of biological and pharmacological properties of polyphenolic compounds such as anti-oxidative, antimicrobial, anti-allergic, anti-diabetic, anti-inflammatory, anti-cancer, chemoprotective, neuroprotective and immunomodulatory effects. Epigallocatechin gallate controls high blood pressure, decreases blood cholesterol and body fat and decreases the risk of osteoporotic...

Preparation and characterisation of monoclonal antibodies against the N protein of the SHpd/2012 strain of porcine epidemic diarrhoea virusOriginal Paper

S.J. Ding, Y.R. Luo, S.T. Zhou, C. Xie, K. Wang, Y.Y. Xie, L. Cui, X.G. Hua, C.L. Yuan, Y.J. Zhou, Z.B. Yang

Vet Med - Czech, 2018, 63(10):468-475 | DOI: 10.17221/23/2018-VETMED  

Porcine epidemic diarrhoea is caused by the porcine epidemic diarrhoea virus, and is a highly contagious disease which affects the intestines of new-born piglets resulting in intense diarrhoea. Historically, the virus has caused enormous economic losses in the pig industry. In particular, the emergence of new epidemic strains means there is a pressing need for prevention and control of the disease. Owing to the specificity of the monoclonal antibodies now available, study of the pathogenesis, immune mechanisms and new diagnostic methods can be performed. In this study, 13 strains of positive hybridoma cells were prepared by immunising mice with purified...

Anatomy of the brachial plexus in the Mongolian gerbil (Meriones unguiculatus Milne-Edwards, 1867)Original Paper

H.N. Araujo Jr, G.B. Oliveira, H.S. Costa, P.M.A. Lopes, R.E.M. Oliveira, F.V.F. Bezerra, C.E.B. Moura, M.F. Oliveira

Vet Med - Czech, 2018, 63(10):476-481 | DOI: 10.17221/78/2017-VETMED  

The Mongolian squirrel is a murine rodent widely used as an experimental model and kept as a pet. With respect to the significance of the brachial plexus, we aimed to describe the origin and the nerves that constitute it, providing new information about the neuroanatomy of this species. Twenty adult animals were used, which were fixed in a 10% formaldehyde solution at the Applied Animal Morphophysiology Laboratory of the Brazilian Federal University of the Semi-Arid Region (UFERSA). The animals were medially incised with an opening of the thoracic cavity, and then bilateral dissection was carried out. Once the nerves were identified, cotton wool soaked...

Urocystitis, pyelonephritis, renal papillary necrosis and chronic tubulointerstitial disease causing chronic renal insufficiency in a Siberian tiger (Panthera tigris altaica): a case reportCase Report

S.W. Lee, A.K. Elfadl, M.J. Chung, H.M. Arif Ullah, D.K. Yuh, S.H. Lee, K.S. Jeong, J.K. Park

Vet Med - Czech, 2018, 63(10):482-487 | DOI: 10.17221/132/2017-VETMED  

The present case report describes a case of chronic renal failure characterised by renal medullary fibrosis and renal papillary necrosis in a male Siberian tiger (Panthera tigris altaica). A 12-year-old male Siberian tiger presented with depression, anorexia and weight loss. Blood urea nitrogen (> 50.4 mmol/l) and ammonia (71.7 µmol/l) were increased, suggesting chronic renal failure and uraemia. The tiger died secondary to gastric haemorrhage. At necropsy, the kidneys had yellow lesions in the medulla and renal papillae and petechiae in the cortex. The stomach had multiple mucosal ulcers and haemorrhage. Microscopically, marked renal...