Veterinární medicína, 2025 (vol. 70), issue 8
SOD1 and CAT gene expressions in stray and owned animalsOriginal Paper
G Sonmez, MC Temizkan, MH Culha
Vet Med - Czech, 2025, 70(8):273-278 | DOI: 10.17221/12/2025-VETMED 
Dogs and cats are the most common companion animals in urban environments. Some dogs and cats live in stable home settings, receiving regular care. However, stray dogs and cats are exposed to chronic stress due to life on the streets or in shelters. Stress is correlated with oxidative stress. The dysregulation of redox balance can lead to the accumulation of reactive oxygen species, which promote cellular and molecular damage. In this study, the blood samples were collected from 150 female animals (90 dogs and 60 cats) to isolate peripheral blood mononuclear...
Cytotoxic and apoptotic effects of etoposide and ellagic acid alone or with possible synergistic/additive combinations on a canine D-17 osteosarcoma cell lineOriginal Paper
GS Ekren Asici, F Kiral, A Bildik, PA Ulutas
Vet Med - Czech, 2025, 70(8):279-293 | DOI: 10.17221/24/2025-VETMED
Osteosarcoma (OSA) is the most prevalent and aggressive malignancy of canine bones. Etoposide is an effective chemotherapeutic agent for cancer treatment, whereas ellagic acid is a naturally occurring compound with antioxidant and anticancer properties; however, both are inhibitors of the topoisomerase enzyme. In this study, the synergistic/additive effect of etoposide, known to have a growth-inhibitory impact in canine osteosarcoma (OSA) cells, and ellagic acid was investigated. The mechanism by which this effect inhibits cell growth at lower etoposide doses was also...
Haemotropic Mycoplasma species in cat blood samples by PCROriginal Paper
O Gulaydin, M Yesilyurt, G Akgul, O Erdeger, K Eercan
Vet Med - Czech, 2025, 70(8):294-301 | DOI: 10.17221/7/2025-VETMED
Haemotropic mycoplasmas can cause severe anaemia in pets and also have zoonotic potential. The determination of these microorganisms from clinical samples is of critical importance. In this study, the presence of Mycoplasma haemofelis (Mhf), Candidatus Mycoplasma haemominutum (CMhm), and Candidatus Mycoplasma turicensis (CMt) in blood samples collected from 62 cats was investigated. Haemotropic mycoplasmas were identified by PCR amplifying the 16S rRNA gene, and sequence analysis was applied for confirmation and differentiation of the species. Six (9.67%) blood samples...
Conduction block and thin and hypokinetic myocardial segments in feline hypertrophic cardiomyopathyCase Report
Y Sung, J Park, Y Chae, T Yun, BT Kang, H Kim
Vet Med - Czech, 2025, 70(8):302-306 | DOI: 10.17221/14/2025-VETMED
A 12-year-old castrated male domestic shorthair cat was referred for respiratory distress. Physical examination revealed a systolic heart murmur at the left apex and crackles in all lung fields. Thoracic radiography showed Valentine-shaped cardiomegaly, pulmonary oedema, and pleural effusion. Echocardiography revealed focal thickening of the interventricular septum [11.01 mm; reference interval (RI) = 3.00–5.20 mm] and left ventricular posterior wall (7.41 mm; RI = 3.00–5.10 mm) during diastole. In the apex region, the free wall was focally thinned to approximately...