Veterinární medicína, 2025 (vol. 70), issue 11
Seasonal dynamics and nutritional risk factors of gastric ulcers in fattening pigs: Results from a one-year field study in SlovakiaOriginal Paper
Z Krepelkova, K Bardova, F Zigo, A Csorgo, J Novotny
Vet Med - Czech, 2025, 70(11):393-400 | DOI: 10.17221/44/2025-VETMED 
This study aimed to comprehensively evaluate the prevalence, severity, and risk factors associated with gastric lesions in fattening pigs across all four seasons in Slovakia. A total of 1 944 porcine stomachs were examined post-mortem at commercial slaughterhouses, focusing on the non-glandular region (pars oesophagea). A macroscopic evaluation was conducted using a standardised scoring system (0–3), in which gastric lesions, including parakeratosis, erosions, and ulcerations, were observed in 48% of the examined stomachs. Significant seasonal variation was detected, with the highest lesion prevalence recorded during the summer months,...
Efficacy of a new ready-to-use PCV2 and Mycoplasma hyopneumoniae vaccine under field conditionsOriginal Paper
P Trampus, A Csagola, T Szalai, N Palmai, A Toth, N Terenyi, Z Nagy, NA Szeplaki, G Somogyi, E Rausch, Z Penzes, R Krejci
Vet Med - Czech, 2025, 70(11):401-407 | DOI: 10.17221/25/2025-VETMED
Coinfection of porcine circovirus type 2 (PCV2) with Mycoplasma hyopneumoniae (M. hyo) causes major worldwide economic losses within the swine industry. This study aimed to assess the safety and efficacy of a single dose of a bivalent vaccine containing PCV2d and M. hyo antigen (Cirbloc® M Hyo) under field conditions. Two studies were performed under the GCP (Good Clinical Practice) requirements on farrow-to-finish farms in Hungary and Cyprus. On both farms, the presence of both PCV2 and M. hyo infection was demonstrated. For both studies, safety parameters were observed...
Coagulation profile in bitches with pyometra: Standard tests and thromboelastographyOriginal Paper
A Ramesova, K Machackova, I Vanova, M Lacinova, A Bartoskova, R Novotny, R Vitasek, K Rehakova, J Doubek
Vet Med - Czech, 2025, 70(11):408-416 | DOI: 10.17221/16/2025-VETMED
This study aimed to determine coagulation changes in bitches with pyometra based on a series of coagulation tests and thromboelastography (TEG), and to assess the incidence of disseminated intravascular coagulation (DIC). Eighteen bitches with pyometra and thirty-four control bitches were examined. Haematological, biochemical, and following haemostasis parameters were measured, including: prothrombin time (PT), activated partial thromboplastin time (aPTT), antithrombin activity (AT), and levels of fibrinogen (FBG), d-dimers (DD), tissue factor (TF), plasminogen (PLG), tissue plasminogen activator inhibitor 1 (TPAI-1), and thromboelastography. DIC was...
Experimental ultrasound stimulator for improving the diffusion of exosomes and drugs into lung tissueOriginal Paper
J Prucha, J Skopalik, T Parak, P Bratka, J Cuprova
Vet Med - Czech, 2025, 70(11):417-426 | DOI: 10.17221/41/2025-VETMED
Pulmonary fibrosis is not only a consequence of the recent COVID-19 pandemic, but is increasingly recognised by both human and veterinary healthcare providers. Pulmonary fibrosis is a progressive condition that leads to a decline in respiratory function and even death. In this work, we compared MSC-derived exosomes with conventional anti-inflammatory drug treatments. Exosomes from stimulated MSCs displayed higher miRNA concentrations (in particular, miRNA-30b was significantly increased). A set of rats with induced lung fibrosis were divided into four groups: NC (control – no treatment), A2 (exosome infusion), A3 (exosome infusion combined with...