Veterinární medicína, 2026 (vol. 71), issue 3
Establishment of an experimental pig model for the induction of a Staphylococcus hyicus skin infectionOriginal Paper
K Matiaskova, M Reichelova, E Jeklova, M Zouharova, S Kobzova, K Nedbalcova, J Matiasovic, M Faldyna
Vet Med - Czech, 2026, 71(3):83-94 | DOI: 10.17221/68/2025-VETMED 
Staphylococcus hyicus is one of the causative agents of exudative epidermitis in pigs. The aim of this study was to establish a porcine challenge model of a skin infection caused by S. hyicus to assess the effectiveness of a medicinal product intended for local application. Based on the results of the presence of toxin encoding genes and antimicrobial resistance (detected resistance to clindamycin, penicillin, ampicillin, erythromycin and tetracycline), three field strains were selected for the trial. At D0, six surface defects were created on the back of six piglets. The defects were inoculated with bacteria at two different concentrations:...
Influence of the drone brood homogenate on the gut integrity and cellular immunity: A pilot study on pigsOriginal Paper
V Karaffova, D Mudronova, M Levkut, L Rajcakova, Erik Hudec, R Zitnan, P Patras
Vet Med - Czech, 2026, 71(3):95-105 | DOI: 10.17221/98/2025-VETMED
Drone brood homogenate (DBH), a nutrient-rich bee product, has received limited scientific attention despite its potential immunomodulatory and gut-protective properties. This study evaluated the effects of a dietary DBH supplementation on the intestinal barrier–related gene expression, phagocytic activity, and lymphocyte subpopulations in pigs. Eighteen weaned pigs were assigned to three groups (control, DBH100, DBH200) and fed DBH at 0, 100, or 200 mg/kg feed for 18 days. The gene expression of tight junction markers (occludin, claudin-1) and mucosal integrity–associated proteins (lumican, OLFM4) was assessed in the ileum by qRT-PCR....
Pulsed electromagnetic fields vs NSAID therapy in canine osteoarthritis: A randomised comparative pilot studyOriginal Paper
S Sassaroli, F Dini, V Sisti, V Riccio, S Meggiolaro, L Bellodi, A Palumbo Piccionello
Vet Med - Czech, 2026, 71(3):106-116 | DOI: 10.17221/54/2025-VETMED
Non-steroidal anti-inflammatory drugs (NSAIDs) are a cornerstone in the management of canine osteoarthritis (OA), despite concerns regarding their long-term safety. Among non-pharmacological alternatives, pulsed electromagnetic field (PEMF) therapy has gained attention for its potential analgesic and anti-inflammatory effects, although veterinary-specific evidence remains limited. This randomised, controlled pilot study compared the clinical efficacy of PEMF therapy versus NSAID treatment (Mavacoxib) in 16 dogs with clinically and radiographically confirmed OA. Dogs were randomly assigned to receive either a 12-session PEMF protocol over 45 days or a standard...
Secondary antibody therapy outperforms corticosteroids in an ameliorating lipopolysaccharide-induced rat model of premature ovarian failureOriginal Paper
AA Zaki, SM Albarrak
Vet Med - Czech, 2026, 71(3):117-128 | DOI: 10.17221/66/2025-VETMED
Premature ovarian failure (POF) is a significant cause of infertility and is often linked to autoimmune aetiologies. Lipopolysaccharide (LPS)-induced inflammation is a well-established model of autoimmune POF in rodents. Immunomodulatory treatments involving corticosteroids, frankincense, and targeted secondary antibodies have been hypothesised to mitigate the autoimmune response, reduce anti-ovarian antibody (AOA) levels, and restore ovarian function in an LPS-induced POF rat model. A POF model was established in female albino rats via the intraperitoneal injection of LPS. The rats were then divided into groups that received no treatment (LPS control),...