Vet Med - Czech, 2010, 55(12):631-635 | DOI: 10.17221/2949-VETMED

Multiple mammary tumours in a bitch: analysis of mitotic index, AgNOR count and c-erbB2 expression status: a case report

P. Kumar, R.V.S. Pawaiya, B.P. Madhu
Indian Veterinary Research Institute, Bareilly, India

This case report of multiple mammary tumours in a Spitz bitch revealed the presence of three tumour masses, T-1, T-2 and T-3, of variable size, shape and texture on different mammary glands. Histopathological examination revealed these tumours to be of different histological type (T-1 - fibrosarcoma, T-2 - malignant mixed mammary tumour and T-3 - papillary adenocarcinoma). The mitotic index and AgNOR count was high in all three tumours indicative of a higher proliferation status of neoplastic cells while T-2 and T-3 showed overexpression of the c-erbB2 oncoprotein.

Keywords: multiple mammary tumours; bitch; c-erbB2; AgNOR

Published: December 31, 2010  Show citation

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Kumar P, Pawaiya RVS, Madhu BP. Multiple mammary tumours in a bitch: analysis of mitotic index, AgNOR count and c-erbB2 expression status: a case report. Vet Med - Czech. 2010;55(12):631-635. doi: 10.17221/2949-VETMED.
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