Vet Med - Czech, 2011, 56(6):314-317 | DOI: 10.17221/1547-VETMED

Human-to-human and human-to-dog Mycobacterium tuberculosis transmission studied by IS6110 RFLP analysis: a case report

M. Moravkova1, M. Slany1, I. Trcka1, M. Havelkova2, J. Svobodova3, M. Skoric4, B. Heinigeova5, I. Pavlik1
1 Veterinary Research Institute, Brno, Czech Republic
2 National Institute of Public Health, Prague, Czech Republic
3 Regional Institute of Public Health, Brno, Czech Republic
4 University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic
5 Hospital Jindrichuv Hradec, Czech Republic

This study reports on the transmission of Mycobacterium tuberculosis of the same IS6110 RFLP type between two acquaintances with open pulmonary tuberculosis and a five-year-old Doberman bitch. No clinical signs, gross lesions at necropsy or histopathological lesions were observed in the infected lungs and gastrointestinal tract of the dog, although M. tuberculosis was directly detected by IS6110 PCR and culture examinations in the respiratory and gastrointestinal tracts. IS6110 PCR positivity in the faeces and blood of the dog poses a risk of M. tuberculosis transmission between the dog and humans.

Keywords: zoonosis; human tuberculosis; pet animal

Published: June 30, 2011  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Moravkova M, Slany M, Trcka I, Havelkova M, Svobodova J, Skoric M, et al.. Human-to-human and human-to-dog Mycobacterium tuberculosis transmission studied by IS6110 RFLP analysis: a case report. Vet Med - Czech. 2011;56(6):314-317. doi: 10.17221/1547-VETMED.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Aranaz A, Liebana E, Pickering X, Novoa C, Mateos A, Dominguez L (1996): Use of polymerase chain reaction in the diagnosis of tuberculosis in cats and dogs. Veterinary Record 138, 276-280. Go to original source... Go to PubMed...
    2. Bonovska M, Tzvetkov Y, Najdenski H, Bachvarova Y (2005): PCR for detection of Mycobacterium tuberculosis in experimentally infected dogs. Journal of Veterinary Medicine Series B, Infectious Diseases and Veterinary Public Health 52, 165-170. Go to original source... Go to PubMed...
    3. Chiu YS, Wang JT, Chang SC, Tang JL, Ku SC, Hung CC, Hsueh PR, Chen YC (2007): Mycobacterium tuberculosis bacteremia in HIV-negative patients. Journal of the Formosan Medical Association 106, 355-364. Go to original source... Go to PubMed...
    4. Gay G, Burbidge HM, Bennett P, Fenwick SG, Dupont C, Murray A, Alley MR (2000): Pulmonary Mycobacterium bovis infection in a dog. New Zealand Veterinary Journal 48, 78-81. Go to original source... Go to PubMed...
    5. Hackendahl NC, Mawby DI, Bemis DA, Beazley SL (2004): Putative transmission of Mycobacterium tuberculosis infection from a human to a dog. Journal of the American Veterinary Medical Association 225, 1573-1577, 1548. Go to original source... Go to PubMed...
    6. Horn B, Forshaw D, Cousins D, Irwin PJ (2000): Disseminated Mycobacterium avium infection in a dog with chronic diarrhoea. Australian Veterinary Journal 78, 320-325. Go to original source... Go to PubMed...
    7. Irwin PJ, Whithear K, Lavelle RB, Parry BW (2000): Acute bronchopneumonia associated with Mycobacterium fortuitum infection in a dog. Australian Veterinary Journal 78, 254-257. Go to original source... Go to PubMed...
    8. Ocepek M, Pate M, Zolnir-Dovc M, Poljak M (2005): Transmission of Mycobacterium tuberculosis from human to cattle. Journal of Clinical Microbiology 43, 3555-3557. Go to original source... Go to PubMed...
    9. Pavlik I (2006): The experience of new European Union Member States concerning the control of bovine tuberculosis. Veterinary Microbiology 112, 221-230. Go to original source... Go to PubMed...
    10. Pavlik I, Trcka I, Parmova I, Svobodova J, Melicharek I, Nagy G, Cvetnic Z, Ocepek M, Pate M, Lipiec M (2005): Detection of bovine and human tuberculosis in cattle and other animals in six Central European countries during the years 2000-2004. Veterinarni Medicina 50, 291-299. http://www.vri.cz/docs/vetmed/50-7-291.pdf Go to original source...
    11. Peters M, Prodinger WM, Gummer H, Hotzel H, Mobius P, Moser I (2007): Mycobacterium tuberculosis infection in a blue-fronted amazon parrot (Amazona aestiva aestiva). Veterinary Microbiology 122, 381-383. Go to original source... Go to PubMed...
    12. Une Y, Mori T (2007): Tuberculosis as a zoonosis from a veterinary perspective. Comparative Immunology Microbiology and Infectious Diseases 30, 415-425. Go to original source... Go to PubMed...
    13. van Embden JD, Cave MD, Crawford JT, Dale JW, Eisenach KD, Gicquel B, Hermans P, Martin C, McAdam R, Shinnick TM (1993): Strain identification of Mycobacterium tuberculosis by DNA fingerprinting: recommendations for a standardized methodology. Journal of Clinical Microbiology 31, 406-409. Go to original source... Go to PubMed...

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY NC 4.0), which permits non-comercial use, distribution, and reproduction in any medium, provided the original publication is properly cited. No use, distribution or reproduction is permitted which does not comply with these terms.


    Return to the content