Vet Med - Czech, 2013, 58(8):389-398 | DOI: 10.17221/6977-VETMED
Contagious caprine pleuropneumonia and its current picture in Pakistan: a reviewReview
- School of Environmental and Rural Science, University of New England, Armidale, Australia
Contagious caprine pleuropneumonia (CCPP) is caused by Mycoplasma capricolum subsp. capripneumoniae (Mccp) which belongs to the Mycoplasma mycoides cluster, a group of five closely related Mycoplasmas, pathogenic to ruminants. The true lesions of CCPP are restricted to the alveolar tissues of infected goats, which distinguish it from other respiratory diseases of small ruminants caused by members of the Mycoplasma mycoides cluster. The typical signs of CCPP are an accumulation of pleural fluid, unilateral hepatisation, adhesions, pleurisy and pleuropneumonia which clearly differentiate it from "MAKePS" syndrome caused by Mycoplasma mycoides subsp. capri (Mmc). The available literature on CCPP shows that so far in Pakistan, the true causative agent (Mccp) of this disease has only been isolated in the Pashin District of Balochistan and that the disease is more frequently confused with other respiratory diseases of goat caused by the Mycoplasma mycoides cluster. The lack of suitable techniques and extensive knowledge in the field is a big limitation for the isolation and characterisation of Mccp from prevailing CCPP-like cases in the goat population of Pakistan.
Keywords: goat; Mycoplasma mycoides cluster; Mycoplasma capricolum subsp. capripneumoniae; diagnostic tests; respiratory diseases
Published: August 31, 2013 Show citation
References
- Abu-Groun EAM, Taylor RR, Varsani H, Wadher BJ, Leach RH, Miles RJ (1994): Biochemical diversity within the mycoplasma-mycoides cluster. Microbiology UK 140, 2033-2042.
Go to original source...
Go to PubMed...
- Adehan RK, Ajuwape ATP, Adetosoye AI, Alaka OO (2006): Characterization of Mycoplasmas isolated from pneumonic lungs of sheep and goats. Small Ruminant Research 63, 44-49.
Go to original source...
- Afzal M (2010): Re-designing smallholder dairy production in Pakistan. Pakistan Veterinary Journal 30, 187- 190.
- Arif A, Schulz J, Thiaucourt F, Taha A, Hammer S (2007): Contagious caprine pleuropneumonia outbreak in captive wild ungulates at al wabra wildlife preservation, state of Qatar. Journal of Zoo and Wildlife Medicine 38, 93-96.
Go to original source...
Go to PubMed...
- Awan MA, Abbas F, Yasinzai M, Nicholas RAJ, Babar S, Ayling RD, Attique MA, Ahmad Z (2009): Prevalence of Mycoplasma capricolum subspecies capricolum and Mycoplasma putrefaciens in goats in Pishin district of Balochistan. Pakistan Veterinary Journal 29, 179-185.
- Awan MA, Abbas F, Yasinzai M, Nicholas RAJ, Babar S, Ayling RD, Attique MA, Ahmad Z, Wadood A, Khan FA (2010): First report of the molecular prevalence of Mycoplasma capricolum subspecies capripneumoniae (Mccp) in goats the cause of contagious caprine pleuropneumonia (CCPP) in Balochistan province of Pakistan. Molecular Biology Reports 37, 3401-3406.
Go to original source...
Go to PubMed...
- Balikci E, Kizil O, Karapinar T, Karahan M, Ozdemir H, Dabak M (2008): Efficacy of marbofloxacin for naturally occurring contagious caprine pleuropneumonia. Small Ruminant Research 77, 75-79.
Go to original source...
- Bascunana CR, Mattsson JG, Bolske G, Johansson KE (1994): Characterization of the 16S rRNA genes from Mycoplasma sp. strain F38 and development of an identification system based on PCR. Journal of Bacteriology 176, 2577-2586.
Go to original source...
Go to PubMed...
- Bolske GB, Mattsson JG, Bascunana CR, Bergstrom K, Wesonga, H, Johansson KE (1996): Diagnosis of contagious caprine pleuropneumonia by detection and identification of Mycoplasma capricolum subsp. capripneumoniae by PCR and restriction enzyme analysis. Journal of Clinical Microbiology 34, 785-791.
Go to original source...
Go to PubMed...
- Bonnet F, Saillard C, Bove JM, Leach RH, Rose DL, Cottew GS, Tully JG (1993): DNA relatedness between field isolates of Mycoplasma F38 group, the agent of contagious caprine pleuropneumonia, and strains of Mycoplasma capricolum. International Journal of Systemic Bacteriology 43, 597-602.
Go to original source...
Go to PubMed...
- Bradbury JM (1983): Phosphatase activity. In: Razin S, Tully JG (eds.): Methods in Mycoplasmology. Vol. 1. Mycoplasma characterization. Academic Press, New York, USA. 363-366.
Go to original source...
- Cetinkaya B, Kalin R, Karahan M, Atil E, Manso-Silvan L, Thiaucourt F (2009): Detection of contagious caprine pleuropneumonia in East Turkey. Revue Scientifique et Technique Office of International Epizootics 28, 1037-1044.
Go to original source...
Go to PubMed...
- Cho HJ, Ruhnke HL, Langford EV (1976): The indirect haemagglutination test for detection of antibodies in cattle narurally infected with mycoplasmas. Canadian Journal of Comparative Medicine 40, 20-29.
Go to PubMed...
- Chu Y, Yan X, Gao P, Zhao P, He Y, Liu J, Lu Z (2011): Molecular detection of a mixed infection of goatpox virus, Orf virus, and Mycoplasma capricolum subsp. capripneumoniae in goats. Journal of Veterinary Diagnostic Investigation 23, 786-789.
Go to original source...
Go to PubMed...
- Cottew GS, Breard A, daMassa AJ, Erno H, Leach RH, Lefevre PC, Rodwell AW, Smith GR (1987): Taxonomy of the Mycoplasma mycoides cluster. Israel Journal of Medical Sciences 23, 632-635. daMassa AJ, Wakenell PS, Brooks D (1992): Mycoplasmas of goats and sheep. Journal of Veterinary Diagnostic Investigation 4, 101-113.
Go to original source...
Go to PubMed...
- De la Fe C, Gomez-Martin A, Amores J, Corrales JC, Sanchez A, Poveda JB, Contreras A (2010): Latent infection of male goats with Mycoplasma agalactiae and Mycoplasma mycoides subspecies capri at an artificial insemination centre. Veterinary Journal 186, 113-115.
Go to original source...
Go to PubMed...
- Dighero MW, Bradstreet PCM, Andrews BE (1970): Dried paper discs for serological identification of human mycoplasmas. Journal of Applied Bacteriology 33, 750-757.
Go to original source...
Go to PubMed...
- Edward DGF (1953): Organisms of the pleuropneumonia group causing disease in goats. Veterinary Record 65, 873-875.
- Erno H (1987): Mycoplasmosis of ruminants: a general introduction. Revue Scientifique et Technique Office of International Epizootics 6, 553-563.
Go to original source...
Go to PubMed...
- Ettorre C, Sacchini F, Scacchia M, Salda LD (2007): Pneumonia of lambs in the Abruzzo region of Italy: Anatomopathological and istopathological studies and localisation of Mycoplasma ovipneumoniae. Veterinaria Italiana 43, 149-155.
Go to PubMed...
- FAO (2012). Online retrieved from: www.disasterriskreduction.net/.../FAO%20disease%20cards%20-%20 CCPP.doc
- Fisher A, Shapiro B, Muriuki C, Heller M, Schnee C, Bongcam-Rudloff E, Vilei EM, Frey J, Jores J (2012): The origin of the Mycoplasma cluster coincides with the domestication of ruminants. PLoS one, e36150.
Go to original source...
- Genesig Standard Kit Handbook HB 10.04.04 (2012): Quantification of Mycoplasma mycoides cluster genomes. Online retrieved from: http://www.primerdesignco.uk/Download%20material/M.mycoides_cluster-Std.pdf
- Giadinis ND, Petridou EJ, Sofianidis G, Filioussis G, Psychas V, Hatzopoulous E, Haratzias H (2008): Mortality in adult goats attributed to Mycoplasma capricolum subspecies capricolum. Veterinary Record 163, 278- 279.
Go to original source...
Go to PubMed...
- Goncalves R, Mariano I, Nunez A, Branco S, Fairfoul G, Nicholas R (2010): Atypical non-progressive pneumonia in goats. Veterinary Journal 183, 219-221.
Go to original source...
Go to PubMed...
- Heldtander M, Wesonga H, Bolske G, Pettersson B, Johansson KE (2001): Genetic diversity and evolution of Mycoplasma capricolum subsp. capripneumoniae strains from eastern Africa assessed by 16S rDNA sequence analysis. Veterinary Microbiology 78, 13-28.
Go to original source...
Go to PubMed...
- Hernandez L, Lopez J, St-Jacques M, Ontiveros L, Acosta J, Handel K (2006): Mycoplasma mycoides subsp. capri associated with goat respiratory disease and high flock mortality. Canadian Veterinary Journal 47, 366-369.
- Hussain R, Auon M, Khan A, Khan, MZ, Mahmood F, Rehman S (2012): Contagious caprine pleuropneumonia in Beetal goats. Tropical Animal Health and Production 44, 477-481.
Go to original source...
Go to PubMed...
- Ishaque SM (1993): Sheep management systems. In: Mackintosh J.B. (ed.): Sheep production in Pakistan. Pakistan Agricultural Research Council, Islamabad, Pakistan.
- Jonas AM, Barber TI (1969): Mycoplasma mycoides var. capri isolated from a goat in Connecticut. Journal of Infectious Diseases 119, 126-131.
Go to original source...
Go to PubMed...
- Jones GE (1989): Contagious caprine pleuropneumonia. Technical Series Office of International Epizootics No. 9, 63.
- Jones GE (1992): Contagious caprine pleuropneumonia. In: Truszcynsky M, Pearson J, Edwards S (eds.): The OIE manual of standards for Diagnostic Tests and Vaccines. Revue Scientifique et Technique Office of International Epizootics. Paris. 376-392.
- Jones GE, Wood AR (1988): Microbiological and serological studies on caprine pneumonias in Oman. Research in Veterinary Science 44, 125-131.
Go to original source...
Go to PubMed...
- Kaliner G, MacOwan KJ (1976): The pathology of experimental and natural contagious caprine pleuropneumonia in Kenya. Journal of Veterinary Medicine Series B 23, 652-661.
Go to original source...
Go to PubMed...
- Khan FM (2010): Participatory appraisal and scanning surveillance based contagious diseases risk profile of District Rahim Yar Khan (Pakistan). Pakistan Veterinary Journal 30, 198-202.
- Leach RH, Erno H, MacOwan, KJ (1993): Proposal for designation of F38-type caprine mycoplasmas as Mycoplasma capricolum subsp. capripneumoniae subsp. nov. and consequent obligatory relegation of strains currently classified as M. capricolum (Tully, Barile, Edward, Theodore, and Erno 1974) to an additional new subspecies, M. capricolum subsp. capricolum subsp. nov. International Journal of Systematic Bacteriology 43, 603-605.
Go to original source...
Go to PubMed...
- Litamoi JK, Lijodi FK, Nandokha E (1989): Contagious caprine pleuropneumonia: some observations in a field vaccination trial using inactivated Mycoplasma strain F38. Tropical Animal Health and Production 21, 146- 150.
Go to original source...
Go to PubMed...
- Litamoi JK, Wanyangu SW, Siman PK (1990): Isolation of Mycoplasma biotype F38 from sheep in Kenya. Tropical Animal Health and Production 22, 260-262.
Go to original source...
Go to PubMed...
- Littlejonhns IR, Cottew GS (1977): The identification of Mycoplasma mycoides subspecies Capri from goats in Australia. Australian Veterinary Journal 53, 297-298.
Go to original source...
Go to PubMed...
- Lorenzon S, Wesonga H, Ygesu L, Tekleghiorgis T, Maikano Y, Angaya M, Hendrikx P, Thiaucourt F (2002): Genetic evolution of Mycoplasma capricolum subsp. capripneumoniae strains and molecular epidemiology of contagious caprine pleuropneumonia by sequencing of locus H2. Veterinary Microbiology 85, 111-123.
Go to original source...
Go to PubMed...
- MacOwan KJ (1976): A mycoplasma from chronic caprine pleuropneumonia in Kenya. Tropical Animal Health and Production 8, 28-36.
Go to original source...
Go to PubMed...
- MacOwan KJ, Minette JE (1977): The role of Mycoplasma strain F38 in contagious caprine pleuropneumonia (CCPP) in Kenya. Veterinary Record 101, 380-381.
Go to original source...
Go to PubMed...
- Manso-Silvan L, Perrier X, Thiaucourt F (2007): Phylogeny of the Mycoplasma mycoides cluster based on analysis of five conserved protein-coding sequences and possible implications for the taxonomy of the group. International Journal of Systematic and Evolutionary Microbiology 57, 2247-2258.
Go to original source...
Go to PubMed...
- Manso-Silvan L, Vilei EM, Sachse K, Djordjevic SP, Thiaucourt F, Frey J (2009): Mycoplasma leachii sp. nov. as a new species designation for Mycoplasma sp. bovine group 7 of Leach, and reclassification of Mycoplasma mycoides subsp. mycoides LC as a serovar of Mycoplasma mycoides subsp. capri. International Journal of Systematic and Evolutionary Microbiology 59, 1353-1358.
Go to original source...
Go to PubMed...
- Manso-Silvan L, Dupuy V, Chu Y, Thiaucourt F (2011): Multi-locus sequence analysis of Mycoplasma capricolum subsp. capripneumoniae for the molecular epidemiology of Contagious caprine pleuropneumonia. Veterinary Research 42, 1-10.
Go to original source...
Go to PubMed...
- March JB, Harrison JC, Borich SM (2002): Humoral immune responses following experimental infection of goats with Mycoplasma capricolum subsp. capripneumoniae. Veterinary Microbiology 84, 29-45.
Go to original source...
Go to PubMed...
- McMartin DA, MacOwan KJ, Swift LL (1980): A century of classical contagious pleuropneumonia: fromo original description to aetiology. British Veterinary Journal 136, 507-515.
Go to original source...
Go to PubMed...
- MPEG (Mycoplasma Experience Product Guide) (2012). Online retrieved from: http://www.mycoplasma-exp.com/diaprogd.htm
- Mondal D, Pramanik A, Basak DK (2004): Clinic-haematology and pathology of caprine mycoplasmal pneumonia in rain fed tropics of Wst Bengal. Small Ruminant Research 51, 285-295.
Go to original source...
- Monnerat MP, Thiaucourt F, Nicolet J, Frey J (1999): Comparative analysis of the lppA locus in Mycoplasma capricolum subsp capricolum and Mycoplasma capricolum subsp. capripneumoniae. Veterinary Microbiology 69, 157-172.
Go to original source...
Go to PubMed...
- Muthomi EK, Rurangirwa FR (1983): Passive haemagglutination and complement fixation as diagnostic tests for contagious caprine pleuropneumonia caused by the F-38 strain of mycoplasma. Research in Veterinary Science 35, 1-5.
Go to original source...
Go to PubMed...
- Nicholas RAJ (2002a): Contagious caprine pleuropneumonia. International Veterinary Information Service, Ithaca, New York, USA.
- Nicholas RAJ (2002b): Improvements in the diagnosis and control of diseases of small ruminants caused by mycoplasmas. Small Ruminant Research 45, 145-149.
Go to original source...
- Nicholas R, Churchward C (2012): Contagious caprine pleuropneumonia: a new aspencts of an old disease. Transboundary and Emerging Diseases 59, 189-196.
Go to original source...
Go to PubMed...
- Noah EY, Kusiluka LJM, Wambura P, Kimera SI (2011): Field isolation of Mycoplasma capripneumoniae in central zone of Tanzania. International Journal of Animal and Veterinary Advances 3, 434-442.
- OIE (2008): Contagious caprine pleuropneumonia. Manual of standards for diagnostic tests and vaccines. Office of International Epizootics, Paris. 1000-1012.
- OIE (2009): Contagious caprine pleuropneumonia. Online retrieved from: http://www.oie.int/fileadmin/Home/eng/Animal_Health_in_the_World/docs/pdf/CONTAGIOUS_CAPRINE_PLEURO_FINAL.pdf
- Ongor H, Kalin R, Acik MN (2011): Detection of Mycoplasma ovipneumoniae from goats with nasal discharge by culture and polymerase chain reaction. Pakistan Veterinary Journal 31, 244-248.
- Ostrowski S, Thiaucourt F, Amirbekov M, Mahmadshoev A, Manso-Silvan L, Dupuy V, Vahobov D, Ziyoev O, Michel S (2011): Fatal outbreak of Mycoplasma capricolum pneumonia in endangered markhors. Emerging Infectious Diseases 17, 2338-2341.
Go to original source...
Go to PubMed...
- Ozdemir U, Loria GR, Godinho KS, Samson R, Rowan TG, Churchward C, Ayling RD, Nicholas RAJ (2006): Effect of danofloxacin (Advocin A180) on goats affected with contagious caprine pleuropneumonia. Tropical Animal Health and Production 38, 533-540.
Go to original source...
Go to PubMed...
- Rahman SU, Siddique M, Hussain I, Muhammad K, Rasool MH (2003): Standardization of indirect haemagglutination test for monitoring Mycoplasma mycoides subspecies capri antibodies raised in rabbits and goats. International Journal of Agriculture and Biology 5, 295-297.
- Rahman SU, Siddique M, Rassol MH (2006): Seroprevalence of Mycoplasma mycoides sub species capri in ruminants and camel. Small Ruminant Research 63, 28-31.
Go to original source...
- Razin S, Barile MF, Harasawa R, Amikam D, Glaser G (1983): Characterization of the mycoplasma genome. Yale Journal of Biology and Medicine 56, 357-366.
- Rice P, Houshaymi BM, Nicholas RAJ, Miles RJ (2000): A rapid biochemical test to aid identification of Mycoplasma mycoides subsp. mycoides small colony (SC) strains. Letters in Applied Microbiology 30, 70-74.
Go to original source...
Go to PubMed...
- Robinson DT, Bebear C (1997): Antibiotic susceptibilities of mycoplasmas and treatment of mycoplasmal infections. Journal of Antimicrobial Chemotherapy 40, 622-630.
Go to original source...
Go to PubMed...
- Rosendal S, Black FT (1972): Direct and indirect immunofluorescence of unfixed and fixed mycoplasma colonies. Acta Pathologica et Microbiologica Scandinavica Section B, Microbiology and Immunology 80, 615-622.
Go to original source...
Go to PubMed...
- Rurangirwa FR (1996): Contagious caprine pleuropneumonia. In: Manual of Standards for Diagnostic Tests and Vaccines. Office of International Epizootics, Paris. 374-383.
- Rurangirwa FR, McGuire TC (2012): Contagious caprine pleuropneumonia: Diagnosis and control. Online retrieved from http://www.fao.org/wairdocs/ilri/x5473b/x5473b11.htm#TopOfPage
- Rurangirwa FR, Masiga WN, Muriu DN, Muthomi E, Murila G, Kagumba M, Nandhoka E (1981): Treatment of contagious caprine pleuro-pneumonia. Tropical Animal Health and Production 13, 177-182.
Go to original source...
Go to PubMed...
- Sadique U, Chaudhry ZI, Younus M, Anjum AA, Idrees M, Qureshi MS, Sajid A, Hassan ZU, Mushtaq M, Subtain SM (2012a): Clinico-pathological study of contagious caprine pleuropneumonia (CCPP) in small ruminants. Journal of Animal and Plant Sciences 22, 45-50.
- Sadique U, Chaudhry ZI, Younus MR, Anjum AA, Hassan Z, Sajid A, Mushtaq M (2012b): Pathogenesis and immunohistochemical studies of caprine pleuropneumonia in experimentally infected goats. Pakistan Veterinary Journal 32, 427-731.
- Sadique U, Chaudhry ZI, Younas M, Anjum AA, Hassan ZU, Idrees M, Mushtaq M, Sajid A and Sabtain SM (2012c): Molecular characterization of contagious caprine pleuropneumonia (CCPP) in small ruminants of Khyberpakhtunkhwa, Pakistan. Journal of Animal and Plant Sciences 22, 33-37.
- Srivastava AK, Meenowa D, Barden G, Salguero FJ, Churchward C, Nicholas RA (2010): Contagious caprine pleuropneumonia in Nauritius. Veterinary Record 167, 304-305.
Go to original source...
Go to PubMed...
- Tariq MA (1980): Studies on the incidence, epizootology and development of effective vaccines for the control of contagious caprine pleuropneumonia, contagious agalactia in sheep and goats in Balochistan. Annual Report, Livestock Department, Govt of Balochistan, Quetta, Pakistan.
- Taylor TK, Bashiruddin JB, Gould AR (1992): Relationships between members of the Mycoplasma mycoides cluster as shown by DNA probes and sequence analysis. International Journal of Systematic Bacteriology 42, 593-601.
Go to original source...
Go to PubMed...
- Thiaucourt F, Bolske G (1996): Contagious caprine pleuropneumonia and other pulmonary mycoplasmoses of sheep and goats. Revue Scientifique et Technique Office of International Epizootics 15, 1397-1414.
Go to original source...
Go to PubMed...
- Thiaucourt F, Bolske G, Leneguersh G, Smith D, Wesonga H (1996): : Diagnosis and control of contagious caprine pleuropneumonia. Revue Scientifique et Technique Office of International Epizootics 15, 1415-1429.
Go to original source...
Go to PubMed...
- Thiaucourt F, Manso-Silvan L, Salah W, Barbe V, Vacherie B, Jacob D, Breton M, Dupuy V, Lomenech AM, Blanchard A, Sirand-Pugnet P (2011): BMC Genomics 12, 114.
Go to original source...
Go to PubMed...
- van Belkum A, Tassios PT, Dijkshoorn L, Haeggman S, Cookson B, Fry NK, Fussing V, Green J, Feil E, GernerSmidt P, Brisse S, Struelens M (2007): European Society of Clinical Microbiology and Infectious Diseases (ESCMID). Study Group on Epidemiological Markers (ESGEM). Clinical Microbiology and Infection 13, 1-46.
Go to original source...
Go to PubMed...
- Wamwayi HM, Wafula JS, Litamoi JK, Nandokha EN (1989): Detection of antibody to mycoplasma F38 in goat sera by an enzyme-linked immunosorbent assay. Tropical Animal Health and Production 21, 43-49.
Go to original source...
Go to PubMed...
- Wesonga HO, Litamoi JK, Kagumba M, Wakhusama E (1993): Relationship between clinical signs and early lesions of contagious caprine pleuropneumonia caused by Mycoplasma strain F38. Small Ruminant Research 10, 45-54.
Go to original source...
- Woubit S, Lorenzon S, Period A, Manso-Silvan L, Thiaucourt F (2004): A specific PCR for the identification of Mycoplasma capricolum subsp. capripneumoniae, the causative agent of contagious caprine pleuropneumonia (CCPP). Veterinary Microbiology 104, 125-132.
Go to original source...
Go to PubMed...
- Zahur AB, Irshad H, Hussain M, Anjum R, Khan MQ (2006): Transboundary Animal Diseases in Pakistan. Journal of Veterinary Medicine, Series B 53, 19-22.
Go to original source...
This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY NC 4.0), which permits non-comercial use, distribution, and reproduction in any medium, provided the original publication is properly cited. No use, distribution or reproduction is permitted which does not comply with these terms.