Vet Med - Czech, 2015, 60(8):460-467 | DOI: 10.17221/8422-VETMED

Necrotising fasciitis, a potential threat following conservative treatment of a leucopenic cat: a case reportCase Report

T. Plavec1, I. Zdovc1, P. Juntes1, T. Svara1, I. Ambrozic-Avgustin2, S. Suhadolc-Scholten1
1 Veterinary Faculty, University of Ljubljana, Ljubljana, Slovenia
2 Biotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia

An eight-month-old, not vaccinated, intact male domestic shorthair cat from a multi-cat household was presented at the clinic because of fever, inappetence and listlessness. Although leucopenic, it was first treated with antibiotics and subcutaneous fluid administration. After several days of hospitalisation with only symptomatic treatment, it developed a vast area of skin necrosis and was consequently euthanised. Necropsy was performed revealing morphological lesions consistent with necrotising fasciitis (NF). Three multidrug resistant bacteria were isolated from the tissue.

Keywords: cat; necrotising fasciitis; immunosuppression; ESBL; MRSH; HLAR

Published: August 31, 2015  Show citation

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Plavec T, Zdovc I, Juntes P, Svara T, Ambrozic-Avgustin I, Suhadolc-Scholten S. Necrotising fasciitis, a potential threat following conservative treatment of a leucopenic cat: a case report. Vet Med - Czech. 2015;60(8):460-467. doi: 10.17221/8422-VETMED.
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References

  1. Allender MC, McCain SL, Ramsay EC, Schumacher J, Ilha MRS (2009): Cervical necrotizing fasciitis and myositis in a western lowland gorilla (Gorilla gorilla gorilla). Journal of Medical Primatology 38, 156-159. Go to original source... Go to PubMed...
  2. Bancroft-Hunt JB, Weston JF, Munday JS (2010): Necrotising fasciitis in a bull due to infection with Arcanobacterium haemolyticum. New Zealand Veterinary Journal 58, 260- 264. Go to original source... Go to PubMed...
  3. Berube DE, Whelan MF, Tater KC, Bracker KE (2010): Fournier's gangrene in a cat. Journal of Veterinary Emergency and Critical Care 20, 148-154. Go to original source... Go to PubMed...
  4. Bishop EJ, Shilton C, Benedict S, Kong F, Gilbert GL, Gal D, Godoy D, Spratt BG, Currie BJ (2007): Necrotizing fasciitis in captive juvenile Crocodylus porosus caused by Streptococcus agalactiae: an outbreak and review of the animal and human literature. Epidemiology and Infection 135, 1248-1255. Go to original source... Go to PubMed...
  5. Boerlin P, Eugster S, Gaschen F, Straub R, Schawalder P (2007): Transmission of opportunistic pathogens in a veterinary teaching hospital. Veterinary Microbiology 82, 347-359. Go to original source... Go to PubMed...
  6. Brachelente C, Wiener D, Malik Y, Huessy D (2007): A case of necrotizing fasciitis with septic shock in a cat caused by Acinetobacter baumannii. Veterinary Dermatology 18, 432-438. Go to original source... Go to PubMed...
  7. Branger C, Zamfir O, Geoffroy S, Laurans G, Arlet G, Thien HV, Gouriou S, Picard B, Denamur E (2005): Genetic background of Escherichia coli and extended-spectrum β-lactamase type. Emerging Infectious Diseases 11, 54-61. Go to original source... Go to PubMed...
  8. Brown MR, Rogers KS (2001): Neutropenia in dogs and cats: a retrospective study of 261 cases. Journal of the American Animal Hospital Association 37, 131-139. Go to original source... Go to PubMed...
  9. Burch DM, Barreiro TJ, Vanek VW (2007): Fournier's gangrene: be alert for this medical emergency. Official Journal of the American Academy of Physician Assistants 20, 44-47. Go to original source... Go to PubMed...
  10. Clermont O, Bonacorsi S, Bingen E (2000): Rapid and simple determination of the Escherichia coli phylogenetic group. Applied and Environmental Microbiology 66, 4555-4558. Go to original source... Go to PubMed...
  11. Cox HU, Hoskins JD, Newman SS, Turnwald GH, Foil CS, Roy AF, Kearney MT (1985): Distribution of staphylococcal species on clinically healthy cats. American Journal of Veterinary Research 46, 1824-1828.
  12. Csiszer AB, Towle HA, Daly CM (2010): Successful treatment of necrotizing fasciitis in the hind limb of a Great Dane. Journal of the American Animal Hospital Association 46, 433-438. Go to original source... Go to PubMed...
  13. Cunningham JD, Silver L, Rudikoff D (2001): Necrotizing fasciitis: a plea for early diagnosis and treatment. Mount Sinai Journal of Medicine 68, 253-261.
  14. DeWinter LM, Low DE, Prescott JF (1999): Virulence of Streptococcus canis from canine streptococcal toxic shock syndrome and necrotizing fasciitis. Veterinary Microbiology 70, 95-110. Go to original source... Go to PubMed...
  15. DiBartola SP, Bateman S (2006): Introduction to fluid therapy. In: DiBartola SP (ed.): Fluid, Electrolyte and Acid-Base Disorders in Small Animal Practice. 3rd ed. Saunders Elsevier, St. Louis, MO. 325-344. Go to original source...
  16. Dierikx CM, van Duijkeren E, Schoormans AHW, van EssenZandbergen A, Veldman K, Kant A, Huijsdens XW, van der Zwaluw K, Wagenaar JA, Mevius DJ (2012): Occurrence and characteristics of extended-spectrum-β-lactamase- and AmpC-producing clinical isolates derived from companion animals and horses. Journal of Antimicrobial Chemotherapy 67, 1368-1374. Go to original source... Go to PubMed...
  17. Elliott DC, Kufera JA, Myers RA (1996): Necrotizing soft tissue infections. Risk factors for mortality and strategies for management. Annals of Surgery 224, 672-683. Go to original source... Go to PubMed...
  18. Ewers C, Janssen T, Kiessling S, Philipp HC, Wieler LH (2005): Rapid detection of virulence-associated genes in avian pathogenic Escherichia coli by multiplex polymerase chain reaction. Avian Diseases 49, 269-273. Go to original source... Go to PubMed...
  19. Fox JG, Beaucage CM, Folta CA, Thornton GW (1981): Nosocomial transmission of Serratia marcescens in a veterinary hospital due to contamination by benzalkonium chloride. Journal of Clinical Microbiology 14, 157-160. Go to original source... Go to PubMed...
  20. Girardeau JP, Dalmasso A, Bertin Y, Ducrot C, Bord S, Livrelli V, Vernozy-Rozand C, Martin C (2005): Association of virulence genotype with phylogenetic background in comparison to different seropathotypes of shiga toxinproducing Escherichia coli isolates. Journal of Clinical Microbiology 43, 6098-6107. Go to original source... Go to PubMed...
  21. Hess MO (2009): Necrotising fasciitis due to Prevotella bivia in a cat. Journal of Small Animal Practice 50, 558-560. Go to original source... Go to PubMed...
  22. Igimi S, Atobe H, Tohya Y, Inoue A, Takahashi E, Konishi S (1994): Characterization of the most frequently encountered Staphylococcus sp. in cats. Veterinary Microbiology 39, 255-260. Go to original source... Go to PubMed...
  23. Jackson MW, Panciera DL, Hartmann F (1994): Administration of vancomycin for treatment of ascending bacterial cholangiohepatitis in a cat. Journal of the American Veterinary Medical Association 204, 602-605. Go to original source... Go to PubMed...
  24. Jenkins CM, Winkler K, Rudloss E, Kirby R (2001): Necrotizing fasciitis in a dog. Journal of Veterinary Emergency and Critical Care 11, 299-305. Go to original source...
  25. Johnson JR (2002): Evolution of pathogenic Escherichia coli. In: Donnenberg M (ed.): Escherichia coli: Virulence Mechanism of a Versatile Pathogen. Academic Press, Amsterdam. 55-77. Go to original source...
  26. Johnson JR, Stell AL (2000): Extended virulence genotypes of Escherichia coli strains from patients with urosepsis in relation to phylogeny and host compromise. Journal of Infectious Diseases 181, 261-272. Go to original source... Go to PubMed...
  27. Johnson JR, Delavari P, Kuskowski M, Stell AL (2001): Phylogenetic distribution of extraintestinal virulence-associated traits in Escherichia coli. Journal of Infectious Diseases 183, 78-88. Go to original source... Go to PubMed...
  28. Johnson JR, Kaster N, Kuskowski MA, Ling GV (2003): Identification of urovirulence traits in Escherichia coli by comparison of urinary and rectal E. coli isolates from dogs with urinary tract infection. Journal of Clinical Microbiology 41, 337-345. Go to original source... Go to PubMed...
  29. Johnson JR, Johnston B, Kuskowski MA, Nougayrede JP, Oswald E (2008): Molecular epidemiology and phylogenetic distribution of the Escherichia coli pks genomic island. Journal of Clinical Microbiology 46, 3906-3911. Go to original source... Go to PubMed...
  30. Kemmett K, Williams NJ, Chaloner G, Humphrey S, Wigley P, Humphrey T (2013): The contribution of systemic Escherichia coli infection to the early mortalities of commercial broiler chickens. Avian Pathology: journal of the W.V.P.A 43: 37-42. Go to original source... Go to PubMed...
  31. Kulendra E, Corr S (2008): Necrotising fasciitis with subperiosteal Streptococcus canis infection in two puppies. Veterinary and Comparative Orthopaedics and Traumatology 21, 474-477. Go to original source... Go to PubMed...
  32. Liu YM, Chi CY, Ho MW, Chen CM, Liao WC, Ho CM, Lin PC, Wang JH (2005): Microbiology and factors affecting mortality in necrotizing fasciitis. Journal of Microbiology, Immunology, and Infection 38, 430-435.
  33. Miller CW, Prescott JF, Mathews KA, Betschel SD, Yager JA, Guru V, DeWinter L, Low DE (1996): Streptococcal toxic shock syndrome in dogs. Journal of American Veterinary Medical Association 209, 1421-1426. Go to original source...
  34. Moyaert H, De Graef EM, Haesebrouck F, Decostere A (2006): Acquired antimicrobial resistance in the intestinal microbiota of diverse cat populations. Research in Veterinary Science 81, 1-7. Go to original source... Go to PubMed...
  35. Naidoo SL, Campbell DL, Miller LM, Nicastro A (2005): Necrotizing fasciitis: a review. Journal of American Animal Hospital Association 41, 104-109. Go to original source... Go to PubMed...
  36. Paauw A, Leverstein-van Hall MA, van Kessel KP, Verhoef J, Fluit AC (2009): Yersiniabactin reduces the respiratory oxidative stress response of innate immune cells. PLoS One 4, e8240. Go to original source... Go to PubMed...
  37. Pesavento PA, Bannasch MJ, Bachmann R, Byrne BA, Hurley KF (2007): Fatal Streptococcus canis infections in intensively housed shelter cats. Veterinary Pathology 44, 218-221. Go to original source... Go to PubMed...
  38. Picard B, Garcia JS, Gouriou S, Duriez P, Brahimi N, Bingen E, Elion J, Denamur E (1999): The link between phylogeny and virulence in Escherichia coli extraintestinal infection. Infection and Immunity 67, 546-553. Go to original source... Go to PubMed...
  39. Plavec T, Zdovc I, Juntes P, Svara T, Suhadolc Scholten S, Nemec A, Domanjko Petric A, Tozon N (2008): Necrotizing fasciitis caused by Serratia marcescens after tooth extraction in a Doberman Pinscher: a case report. Veterinarni Medicina 53, 629-635. Go to original source...
  40. Prescott JF, Miller CW, Mathews KA, Yager JA, DeWinter L (1997): Update on canine streptococcal toxic shock syndrome and necrotizing fasciitis. Canadian Veterinary Journal 38, 241-242.
  41. Rosenfeld AJ, Dunphy E (2012): Lecture VI: Fluid therapy. Proceedings of FVMA's 83rd Annual Conference, Florida Veterinary Medical Association, Tampa, 126-147.
  42. Schnelle AN, Barger AM (2012): Neutropenia in dogs and cats: causes and consequences. Veterinary Clinics of North America: Small Animal Practice 42, 111-122. Go to original source... Go to PubMed...
  43. Sparkes AH, Papasouliotis K, Sunvold G, Werrett G, Clarke C, Jones M, Gruffydd-Jones TJ, Reinhart G (1998): Bacterial flora in the duodenum of healthy cats, and effect of dietary supplementation with fructooligosaccharides. American Journal of Veterinary Research 59, 431-435. Go to original source...
  44. Sura R, Hinckley LS, Risatti GR, Smyth JA (2008): Fatal necrotising fasciitis and myositis in a cat associated with Streptococcus canis. Veterinary Record 162, 450-453. Go to original source... Go to PubMed...
  45. Toth I, Herault F, Beutin L, Oswald E (2003): Production of cytolethal distending toxins by pathogenic Escherichia coli strains isolated from human and animal sources: establishment of the existence of a new cdt variant (Type IV). Journal of Clinical Microbiology 41, 4285-4291. Go to original source... Go to PubMed...
  46. Weese JS, Poma R, James F, Buenviaje G, Foster R, Slavic D (2009): Staphylococcus pseudintermedius necrotizing fasciitis in a dog. Canadian Veterinary Journal 50, 655-656.
  47. Wong CH, Chang HC, Pasupathy S, Khin LW, Tan JL, Low CO (2003): Necrotizing fasciitis: clinical presentation, microbiology, and determinants of mortality. Journal of Bone and Joint Surgery. American volume 85-A, 1454-1460. Go to original source...
  48. Woodford N (2010): Rapid characterization of β-lactamases by multiplex PCR. Methods in Molecular Biology 642, 181-192. Go to original source... Go to PubMed...
  49. Worth AJ, Marshall N, Thompson KG (2005): Necrotising fasciitis associated with Escherichia coli in a dog. New Zealand Veterinary Journal 53, 257-260. Go to original source... Go to PubMed...
  50. Zappulli V, Mazzariol S, Cavicchioli L, Petterino C, Bargelloni L, Castagnaro M (2005): Fatal necrotizing fasciitis and myositis in a captive common bottlenose dolphin (Tursiops truncatus) associated with Streptococcus agalactiae. Journal of Veterinary Diagnostic Investigation 17, 617-622. Go to original source... Go to PubMed...

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