Vet Med - Czech, 2021, 66(2):76-79 | DOI: 10.17221/61/2020-VETMED

Primary splenic diffuse large B-cell lymphoma with multinucleated giant cells in a horseCase Report

W Hananeh1, R Al Rukibat1, M Daradka2
1 Department of Veterinary Pathology and Public Health, Faculty of Veterinary Medicine, Jordan University of Science and Technology, Irbid, Jordan
2 Department of Veterinary Clinical Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, Irbid, Jordan

A diagnosis of a diffuse splenic large B-cell lymphoma with multinucleated giant cells in a 5-year-old mare was made based upon the clinical, pathological, and immunohistochemical findings. The enormous primary splenic mass weighed 51.75 kg. To the best of our knowledge, this is the biggest reported splenic mass and the first case of an equine diffuse large B-cell lymphoma with multinucleated giant cells.

Keywords: equine; immunohistochemistry; lymphoma; spleen

Received: March 13, 2020; Accepted: November 10, 2020; Published: February 28, 2021  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Hananeh W, Al Rukibat R, Daradka M. Primary splenic diffuse large B-cell lymphoma with multinucleated giant cells in a horse. Vet Med - Czech. 2021;66(2):76-79. doi: 10.17221/61/2020-VETMED.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Durham AC, Pillitteri CA, San Myint M, Valli VE. Two hundred three cases of equine lymphoma classified according to the World Health Organization (WHO) classification criteria. Vet Pathol. 2013 Jan;50(1):86-93. Go to original source... Go to PubMed...
    2. Meyer J, Delay J, Bienzle D. Clinical, laboratory, and histopathologic features of equine lymphoma. Vet Pathol. 2006 Nov;43(6):914-24. Go to original source... Go to PubMed...
    3. Miglio A, Morelli C, Gialletti R, Lauteri E, Sforna M, Marenzoni ML, Antognoni MT. Clinical and immunophenotypic findings in 4 forms of equine lymphoma. Can Vet J. 2019 Jan;60(1):33-40.
    4. Munoz A, Riber C, Trigo P, Castejon F. Hematopoietic neoplasias in horses: Myeloproliferative and lymphoproliferative disorders. J Equine Sci. 2009;20(4):59-72. Go to original source... Go to PubMed...
    5. Ohshima M, Morita T, Sawada M, Shimada A, Kobayashi H, Sawashima K. B-cell immunoblastic lymphoma with multinucleated giant cells in a cat. J Vet Med Sci. 2004 Feb; 66(2):189-91. Go to original source... Go to PubMed...
    6. Sprayberry KA, Robinson NE. Robinson's current therapy in equine medicine. St. Louis, Missouri: Elsevier Health Sciences; 2014. 998 p.
    7. Suvarna KS, Layton C, Bancroft JD. Bancroft's theory and practice of histological techniques. Amsterdam: Elsevier Health Sciences; 2018. 672 p.
    8. Taintor J, Schleis S. Equine lymphoma. Equine Vet Educ. 2011;23(4):205-13. Go to original source...
    9. Tanimoto T, Yamasaki S, Ohtsuki Y. Primary splenic lymphoma in a horse. J Vet Med Sci. 1994 Aug;56(4):767-9. Go to original source... Go to PubMed...

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY NC 4.0), which permits non-comercial use, distribution, and reproduction in any medium, provided the original publication is properly cited. No use, distribution or reproduction is permitted which does not comply with these terms.


    Return to the content