Vet Med - Czech, 2022, 67(3):150-155 | DOI: 10.17221/136/2020-VETMED

Pulmonary eosinophilic granulomatosis in a dogCase Report

CF Agudelo, L Stehlik, Z Filipejova, B Koskova, M Sterbova, M Crha
Small Animal Clinic, University of Veterinary Sciences Brno, Brno, Czech Republic

A two-year-old female Prague Ratter dog was presented for evaluation of cough, exercise intolerance and worsening dyspnea. A previous treatment with antibiotics did not resolve the clinical signs. A diagnostic approach revealed peripheral eosinophilia, endoscopic bronchial changes, and bronchoalveolar lavage with eosinophilic inflammation. Thoracic radiographs revealed a solitary mass and bilateral interstitial lung pattern. These radiographic findings were confirmed by computed tomography and ultrasound-guided biopsy of the lung mass. Treatment with prednisolone and azathioprine was initiated. Two months afterwards, the granuloma was no longer detectable radiographically. All medication was gradually discontinued after nine months and currently, after almost three years, the dog remains free of clinical signs.

Keywords: allergy; bronchoalveolar lavage; eosinophilia; immunosuppression; tomography

Received: June 24, 2020; Accepted: October 8, 2021; Prepublished online: January 18, 2022; Published: March 15, 2022  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Agudelo C, Stehlik L, Filipejova Z, Koskova B, Sterbova M, Crha M. Pulmonary eosinophilic granulomatosis in a dog. Vet Med - Czech. 2022;67(3):150-155. doi: 10.17221/136/2020-VETMED.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Adamama-Moraitou KK, Soubasis N, Pardali D, Psalla D, Papazoglou LG, Prassinos NN, Anagnostou TL, Rallis TS. Recurrent intraluminal eosinophilic tracheal granuloma in a Siberian Husky. Vet Q. 2015 Jun;35(2):116-22. Go to original source... Go to PubMed...
    2. Akuthota P, Weller PF. Eosinophilic pneumonias. Clin Microbiol Rev. 2012 Oct;25(4):649-60. Go to original source... Go to PubMed...
    3. Campos LEM, Pereira LFF. Pulmonary eosinophilia. J Bras Pneumol. 2009 Jun;35(6):561-73. Go to original source... Go to PubMed...
    4. Confer AW, Qualls CW Jr, MacWilliams PS, Root CR. Four cases of pulmonary nodular eosinophilic granulomatosis in dogs. Cornell Vet. 1983 Jan;73(1):41-51.
    5. DeNault L. A case report: Pulmonary infiltrates with eosinophilia in a canine. Iowa State Univ Vet. 2000;62(1): 20-2.
    6. Fina C, Vignoli M, Terragni R, Rossi F, Wisner E, Saunders JH. Computed tomographic characteristics of eosinophilic pulmonary granulomatosis in five dogs. Vet Radiol Ultrasound. 2014 Jan-Feb;55(1):16-22. Go to original source... Go to PubMed...
    7. Johnson LR, Johnson EG, Hulsebosch SE, Dear JD, Vernau W. Eosinophilic bronchitis, eosinophilic granuloma, and eosinophilic bronchopneumopathy in 75 dogs (2006- 2016). J Vet Intern Med. 2019 Sep;33(5):2217-26. Go to original source... Go to PubMed...
    8. Katajavuori P, Melamies M, Rajamaki MM. Eosinophilic pulmonary granulomatosis in a young dog with prolonged remission after treatment. J Small Anim Pract. 2013 Jan; 54(1):40-3. Go to original source... Go to PubMed...
    9. Mesquita L, Lam R, Lamb CR, McConnell JF. Computed tomographic findings in 15 dogs with eosinophilic bronchopneumopathy. Vet Radiol Ultrasound. 2015 Jan-Feb; 56(1):33-9. Go to original source... Go to PubMed...
    10. Moon M. Pulmonary infiltrates with eosinophilia. J Small Anim Pract. 1992 Jan;33(1):19-23. Go to original source...
    11. Neer TM, Waldron DR, Miller RI. Eosinophilic pulmonary granulomatosis in two dogs and literature review. J Am Anim Hosp Assoc. 1986 Nov;22(56):543-99.
    12. Pornsuriyasak P, Suwatanapongched T, Klaewsongkram J, Buranapraditkun S, Rotjanapan P. Acute respiratory failure secondary to eosinophilic pneumonia following influenza vaccination in an elderly man with chronic obstructive pulmonary disease. Int J Infect Dis. 2014 Sep; 26:14-6. Go to original source... Go to PubMed...
    13. Reinero C. Interstitial lung diseases in dogs and cats part II: Known cause and other discrete forms. Vet J. 2019 Jan; 243:55-64. Go to original source... Go to PubMed...
    14. Sykes JE, Weiss DJ, Buoen LC, Blauvelt MM, Hayden DW. Idiopathic hypereosinophilic syndrome in 3 Rottweilers. J Vet Intern Med. 2001 Mar-Apr;15(2):162-6. Go to original source...
    15. Waddle JR, Giger U, Evans S. Chronic eosinophilic pneumonia in a dog. Can Vet J. 1992 Feb;33(2):126-8.
    16. Wallace M, Lathan P, Brinkman-Ferguson E. What is your diagnosis? Hypereosinophilia in a dog with multicentric B-cell lymphoma. J Am Vet Med Assoc. 2012 May 1; 240(9):1063-5. Go to original source... Go to PubMed...

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY NC 4.0), which permits non-comercial use, distribution, and reproduction in any medium, provided the original publication is properly cited. No use, distribution or reproduction is permitted which does not comply with these terms.


    Return to the content