Vet Med - Czech, 2022, 67(5):257-262 | DOI: 10.17221/17/2021-VETMED

Neuroendocrine carcinoma of the heart base in a dog: A case reportCase Report

Z Filipejova1, CF Agudelo1, B Koskova1, M Sterbova1, M Paninarova1, M Skoric2, M Crha1
1 Small Animal Clinic, Faculty of Veterinary Medicine, University of Veterinary Sciences Brno, Czech Republic
2 Department of Pathological Morphology and Parasitology, Faculty of Veterinary Medicine, University of Veterinary Sciences Brno, Czech Republic

A case of a nine-year-old, intact female, American Bulldog with a heart mass is described. Echocardiography was used to identify this pathological lesion. Part of the mass and pericardial sac were surgically removed for histopathological examination. A final diagnosis of neuroendocrine carcinoma was diagnosed by necropsy and histopathology. To the author's knowledge, there is very limited information in the literature about this pathology.

Keywords: cardiac tumour; echocardiography; heart; histopathology; immunohistochemistry

Received: February 5, 2021; Accepted: October 18, 2021; Prepublished online: January 18, 2022; Published: May 15, 2022  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Filipejova Z, Agudelo C, Koskova B, Sterbova M, Paninarova M, Skoric M, Crha M. Neuroendocrine carcinoma of the heart base in a dog: A case report. Vet Med - Czech. 2022;67(5):257-262. doi: 10.17221/17/2021-VETMED.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Ajithdoss DK, Trainor KE, Snyder KD, Bridges CH, Langohr IM, Kiupel M, Porter BF. Coccidioidomycosis presenting as a heart base mass in two dogs. J Comp Pathol. 2011 Aug-Oct;145(2-3):132-7. Go to original source... Go to PubMed...
    2. Birettoni F, Porciello F, Caivano D, Arcelli R, Sforna M, Antognoni M. Primary neuroendocrine carcinoma of the gallbladder in a dog. Vet Res Commun. 2008 Sep;32 (Suppl_1):S239-42. Go to original source... Go to PubMed...
    3. Brown PJ, Rema A, Gartner F. Immunohistochemical characteristics of canine aortic and carotid body tumours. J Vet Med A Physiol Pathol Clin Med. 2003 Apr;50(3):140-4. Go to original source... Go to PubMed...
    4. De Nijs MI, Vink A, Bergmann W, Szatmari V. Left ventricular cardiac myxoma and sudden death in a dog. Acta Vet Scand. 2016 Jun 22;58(1): [4]. Go to original source... Go to PubMed...
    5. Guajardo-Salinas GE, Anaya-Ayala JE, Rice DC, Moran CA, Reardon MJ. Primary high-grade neuroendocrine carcinoma of the heart. Tex Heart Inst J. 2013;40(1):71-4.
    6. Johnson MS, Martin M, Binns S, Day MJ. A retrospective study of clinical findings, treatment and outcome in 143 dogs with pericardial effusion. J Small Anim Pract. 2004 Nov;45(11):546-52. Go to original source... Go to PubMed...
    7. Joiner KS, Smith AN, Henderson RA, Brawner WR, Spangler EA, Sartin EA. Multicentric cutaneous neuroendocrine (Merkel cell) carcinoma in a dog. Vet Pathol. 2010 Nov;47(6):1090-4. Go to original source... Go to PubMed...
    8. Kerstetter KK, Krahwinkel DJ Jr, Millis DL, Hahn K. Pericardiectomy in dogs: 22 cases (1978-1994). J Am Vet Med Assoc. 1997 Sep 15;211(6):736-40. Go to original source...
    9. Kimura N, Sasano N, Yamada R, Satoh J. Immunohistochemical study of chromograninin 100 cases of pheochromocytoma, carotid body tumour, medullary thyroid carcinoma and carcinoid tumour. Virchows Arch A Pathol Anat Histopathol. 1988;413(1):33-8. Go to original source... Go to PubMed...
    10. MacDonald KA, Cagney O, Magne ML. Echocardiographic and clinicopathologic characterization of pericardial effusion in dogs: 107 cases (1985-2006). J Am Vet Med Assoc. 2009 Dec 15;235(12):1456-61. Go to original source... Go to PubMed...
    11. Morgan E, O'Connell K, Thomson M, Boyd S, Sandy J. Primary hepatic neuroendocrine carcinoma treated with doxorubicin and cyclophosphamide in a dog. J Am Anim Hosp Assoc. 2019 May-Jun;55(3):e55305. Go to original source... Go to PubMed...
    12. Nakahira R, Michishita M, Yoshimura H, Hatakeyama H, Takahashi K. Neuroendocrine carcinoma of the mammary gland in a dog. J Comp Pathol. 2015 Feb-Apr;152 (2-3):188-91. Go to original source... Go to PubMed...
    13. Obradovich JE, Withrow SJ, Powers BE, Walshaw R. Carotid body tumors in the dog. Eleven cases (1978-1988). J Vet Intern Med. 1992 Mar-Apr;6(2):96-101. Go to original source... Go to PubMed...
    14. Ogawa B, Taniai E, Hayashi H, Imaoka M, Machida N, Mitsumori K, Shibutani M. Neuroendocrine carcinoma of the apocrine glands of the anal sac in a dog. J Vet Diagn Invest. 2011 Jul;23(4):852-6. Go to original source... Go to PubMed...
    15. Prange H, Falk-Junge G, Katenkamp D, Schneider E, Zieger M. Zur Verbreitung, Epizootiologie und Rontgendiagnostik intra-thorakaler Geschwulste beim Hund [The distribution, epizootiology and x-ray diagnosis of intrathoracic tumors in the dog]. Arch Exp Veterinarmed. 1988 Sep 1;42(5):637-49. German.
    16. Rajagopalan V, Jesty SA, Craig LE, Gompf R. Comparison of presumptive echocardiographic and definitive diagnoses of cardiac tumors in dogs. J Vet Intern Med. 2013 Sep-Oct;27(5):1092-6. Go to original source... Go to PubMed...
    17. Sako T, Shimoyama Y, Akihara Y, Ohmachi T, Yamashita K, Kadosawa T, Nakade T, Uchida E, Okamoto M, Hirayama K, Taniyama H. Neuroendocrine carcinoma in the nasal cavity of ten dogs. J Comp Pathol. 2005 Aug-Oct;133 (2-3):155-63. Go to original source... Go to PubMed...
    18. Sisson D, Thomas WP, Ruehl WW, Zinkl JG. Diagnostic value of pericardial fluid analysis in the dog. J Am Vet Med Assoc. 1984 Jan 1;184(1):51-5. Go to original source...
    19. Sozmen M, Devrim T, Kuruca N, Inal S, Karaca E, Gulbahar MY. Primary unilateral small cell neuroendocrine carcinoma of the kidney in a dog. J Comp Pathol. 2020 Apr; 176:71-5. Go to original source... Go to PubMed...
    20. Treggiari E, Pedro B, Dukes-Mcewan J, Gelzer AR, Blackwood L. A descriptive review of cardiac tumours in dogs and cats. Vet Comp Oncol. 2017 Jun;15(2):273-88. Go to original source... Go to PubMed...
    21. Ware WA, Hopper DL. Cardiac tumors in dogs: 1982-1995. J Vet Intern Med. 1999 Mar-Apr;13(2):95-103. Go to original source...
    22. Wißt T, Jehn CF, Vierbuchen M, Starekova J. Solitary neuroendocrine carcinoma of the heart: A case report. Eur Heart J Case Rep. 2018 Sep 12;2(3):1-5. Go to original source... Go to PubMed...
    23. Yates WD, Lester SJ, Mills JH. Chemoreceptor tumors diagnosed at the Western College of Veterinary Medicine 1967-1979. Can Vet J. 1980 Apr;21(4):124-9.

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY NC 4.0), which permits non-comercial use, distribution, and reproduction in any medium, provided the original publication is properly cited. No use, distribution or reproduction is permitted which does not comply with these terms.


    Return to the content