Vet Med - Czech, 2022, 67(11):579-584 | DOI: 10.17221/7/2022-VETMED

Acute toxicity of praziquantel to fish Danio rerio and planktonic crustacean Daphnia magnaOriginal Paper

E Zuskova ORCID..., V Piackova, O Valentova, K Zalohova, J Velisek ORCID...
South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in Ceske Budejovice, Ceske Budejovice, Czech Republic

This study evaluated the toxicity of the pyrazino isoquinoline anthelmintic praziquantel (PZQ) to the Danio rerio zebrafish and Daphnia magna water flea. The estimated 24 h and 96 h LC50 of PZQ to the zebrafish was 39.9 mg/l and 30.4 mg/l, respectively. The highest 24 h and 96 h non-lethal concentration (LC0) was 21.7 mg/l and 21.2 mg/l, respectively. The mobility inhibition test of the juvenile Daphnia magna revealed a 48 h EC50 of 42.7 mg/l.

Keywords: 96 h LC50; antiparasitic; bath treatment; water flea; zebrafish

Received: January 18, 2022; Accepted: September 19, 2022; Prepublished online: October 24, 2022; Published: November 1, 2022  Show citation

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Zuskova E, Piackova V, Valentova O, Zalohova K, Velisek J. Acute toxicity of praziquantel to fish Danio rerio and planktonic crustacean Daphnia magna. Vet Med - Czech. 2022;67(11):579-584. doi: 10.17221/7/2022-VETMED.
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