Veterinární medicína - Online first
Efficacy of five peroral therapeutics against Ichthyophthirius multifiliis infestation in salmonidsOriginal Paper
K Matejickova, J Motlova, H Novotna, Z Mikulkova, P Ginterova, M Jerabek, L Pojezdal
Vet Med-Czech, X:X | DOI: 10.17221/99/2025-VETMED 
Ichthyophthirius multifiliis is a widespread parasitic ciliate causing significant losses in intensive freshwater aquaculture. This study evaluated the efficacy of medicated feed containing amprolium hydrochloride (2 mg/kg b.w./day), clopidol (2 mg/kg b.w./day), praziquantel (20 mg/kg b.w./day), toltrazuril (50 mg/kg b.w./day), and doxycycline (40 mg/kg b.w./day) administered at different stages of infection in experimentally infected brook trout fingerlings. Doxycycline and praziquantel demonstrated high protective efficacy (0–5% mortality) when applied during parasite exposure or the preclinical stage of infection. In contrast, amprolium...
An experimental challenge model for infecting African catfish (Clarias gariepinus) with Edwardsiella tardaOriginal Paper
I Toulova, V Vaibarova, I Papezikova, K Matejickova, I Mikulikova, H Novotna, M Palikova
Vet Med-Czech, X:X | DOI: 10.17221/102/2025-VETMED
Edwardsiella tarda is an important fish pathogen that causes outbreaks leading to significant losses in aquacultural species such as African catfish (Clarias gariepinus). In order to study host-pathogen interactions and design preventive strategies, it is essential to prepare a reliable experimental infection model. The aim of this study was to develop a reproducible immersion challenge model for E. tarda infection in C. gariepinus. The present study consisted of preliminary experiments and a main experiment evaluating the different routes of infection and the bacterial concentrations and exposure durations in an immersion...