Veterinární medicína, 2015 (vol. 60), issue 7
Collie eye anomaly: a reviewReview
A. Palanova
Vet Med - Czech, 2015, 60(7):345-350 | DOI: 10.17221/8381-VETMED 
Collie eye anomaly (CEA) is an inherited congenital visual impairment with heterogeneous signs. The first symptoms are already visible in the early embryo. Among the most affected breeds are Collies and Shetland Sheepdogs but the disease has spread to different breeds depending on the country of origin. Dogs affected with this disease share a 7.8 kb deletion in intron 4 of the NHEJ1 gene. Inheritance of this disease is autosomal recessive with incomplete penetrance. Thanks to a commercially available genetic test breeders can identify genetically affected recessive homozygotes and clinically healthy but genetic carriers of the mutation and...
Prophylaxis of post-weaning diarrhoea in piglets by zinc oxide and sodium humateOriginal Paper
M. Trckova, A. Lorencova, K. Hazova, Z. Sramkova Zajacova
Vet Med - Czech, 2015, 60(7):351-360 | DOI: 10.17221/8382-VETMED
The high prophylactic doses of ZnO commonly used to control post-weaning diarrhoea (PWD) in piglets have become an environmental problem. The possibility of partial replacement of ZnO by sodium humate (HNa) in PWD treatment was investigated in this study. Weaned piglets (32) were challenged with two enterotoxigenic E. coli strains (ETEC/O149/F4/LT and ETEC/O147/F18/LT) and allocated into four treatments maintained for three weeks: C (no supplementation); ZnO2.5 (2.5 g ZnO/kg diet); HNa + ZnO1.0; HNa + ZnO1.5; HNa + ZnO1.7 (20 g HNa and 1.0, 1.5 and 1.7 g ZnO/kg diet, respectively). The effects on incidence, severity and duration of diarrhoea,...
Cocaine- and amphetamine-regulated transcript immunoreactive nerve fibres in the mucosal layer of the canine gastrointestinal tract under physiological conditions and in inflammatory bowel diseaseOriginal Paper
A. Rychlik, S. Gonkowski, M. Nowicki, J. Calka
Vet Med - Czech, 2015, 60(7):361-367 | DOI: 10.17221/8383-VETMED
The objective of this study was to determine the effect of canine inflammatory bowel disease (IBD) on the density of cocaine- and amphetamine-regulated transcript (CART) immunoreactive nerve fibres in the mucosa of different sections of the gastrointestinal tract. Fibre density was analysed in mucosal specimens from the duodenum, jejunum and descending colon of healthy dogs and patients with inflammatory bowel disease of varying intensity. Nervous fibres were stained in single-cell immunofluorescence assays. The density of CART-immunoreactive fibres was determined using a semi-quantitative approach by counting the number of fibres in the field of view...
Analyses of anaesthesia with ketamine combined with different sedatives in ratsOriginal Paper
A.M. Molina, M.R. Moyano, J.M. Serrano-Rodriguez, N. Ayala, A.J. Lora, J.M. Serrano-Caballero
Vet Med - Czech, 2015, 60(7):368-375 | DOI: 10.17221/8384-VETMED
The goal of this study was to establish an easy-to-perform, reliable, and safe protocol for intraperitoneal injection anaesthesia in rats, as well as an easy method to assess anaesthesia depth under routine clinical conditions. Seventy Wistar rats (35 males and 35 females) were used to evaluate intraperitoneal anaesthesia with ketamine (75 mg/kg) combined with one of the following central nervous system depressors: acepromazine (2.5 mg/kg), diazepam (5 mg/kg), medetomidine (0.5 mg/kg), midazolam (5 mg/kg) and xylazine (2.5 mg/kg). Significant differences were found between the combinations in ataxia, recovery and righting parameters, as well as respiratory...
A cartilaginous choristoma in a pig liver: a case reportCase Report
N.M. Vuckovic, D.C. Vuckovic, M.I. Urosevic, V.S. Cabarkapa
Vet Med - Czech, 2015, 60(7):376-378 | DOI: 10.17221/8385-VETMED
Choristomas are small aggregates of normal tissue components in aberrant locations, and may be mistaken for true neoplasms. We report a case of an incidentally found mature cartilage island in the portal tract of a two-month old piglet. All other examined organs were normal. The pig belonged to the control group of animals in a short-term experiment, was fed with wheat and corn, and did not receive any external or internal treatment. To the best of our knowledge, this is the first case of a mature cartilaginous choristoma in pig liver.
Equine ocular squamous cell carcinoma: a case reportCase Report
M. Drazek, M. Lew, S. Lew, J. Szarek, I. Balicki, L. Della Salda
Vet Med - Czech, 2015, 60(7):379-386 | DOI: 10.17221/8386-VETMED
An eight-year-old gelding, Wielkopolski Horse was presented with a pink tumour, which filled the entire palpebral fissure of the left eye. Ultrasonography revealed it to be well-demarcated from the cornea mass, which covered its entire surface. Due to the extensive size of the lesion and the lack of owner's consent to post-operative treatment, it was decided to perform enucleation. A histopathological examination revealed corneal squamous cell carcinoma (CSCC). The primary cause of the tumour has not been established. Immunohistochemistry was negative for p16 immunoreactivity which is typical for the E7 oncoprotein in PV infection, and is suspected...
Magnetic resonance imaging: findings of osteochondrosis like-lesions in glenoid fossa and proximal humeral metaphyses in a dog: a case reportCase Report
N. Orellana-Jaimes, M.M. Ginja, F. San Roman-Llorens, M. Garcia-Gomez, M.A. Orden, J.R. Altonaga, J.M. Gonzalo-Orden
Vet Med - Czech, 2015, 60(7):387-390 | DOI: 10.17221/8387-VETMED
Osteochondritis dissecans (OCD) of the humeral head is a common cause of forelimb lameness in dogs. OCD represents the late phase of osteochondrosis (OC). Magnetic resonance imaging (MRI) is a useful technique for detection and characterisation of this disease. The main objective of this study was to show MRI findings of OCD in the humeral head, OC like-lesions in glenoid fossa and proximal humeral metaphyses of a dog. MRI analysis revealed the extent and severity of the inflammatory changes within the subchondral bones in both the glenoid cavity and humeral head. OCD and OC like-lesions were also evaluated in histopathological studies.
Canine mammary anaplastic carcinoma with concurrent aorto-iliac thrombosis in a dog: a case reportCase Report
J.H. Kim, W.J. Kim, J. Park, J.I. Shin, H.Y. Yoon
Vet Med - Czech, 2015, 60(7):391-398 | DOI: 10.17221/8388-VETMED
An 11-year-old, 6.75 kg, spayed female Maltese dog was referred for evaluation of a recurrent mammary gland tumour (MGT) after recent lumpectomies. We performed a regional mastectomy, and the mammary gland tumour was diagnosed as a mammary anaplastic carcinoma. On the 11th postoperative day, the dog presented with a one-day history of lethargy and left hind limb weakness. Increased D-dimer level and two-dimensional and Doppler ultrasonography revealed a unilateral aorto-iliac thrombus. Although prompt thrombolytic drug administration by intravenous infusion was recommended, the owner did not consent to further examination and treatment due...
A car accident involving a restrained dog within the vehicle: a case reportCase Report
M. Zeleny, K. Grusova
Vet Med - Czech, 2015, 60(7):399-402 | DOI: 10.17221/8389-VETMED
The aim of this article is to describe and evaluate a unique car accident involving a pet dog within a car. The unique aspect is the linking and evaluation of information from the veterinary record with a detailed description of the car accident, the driver's injuries, the safety systems used and photographs. This method of complex evaluation of an injury mechanism is commonly used in forensic medicine when evaluating car accidents involving people. The accident is especially unique due to the fact that a dog safety harness was used to restrain the pet dog. The dog suffered severe injuries, whilst the car driver suffered only minor injuries. The conclusion...