Vet Med - Czech, 2014, 59(9):447-452 | DOI: 10.17221/7685-VETMED

Post anaesthetic myelopathy in the horse: a case reportCase Report

M. Patschova, R. Kabes, E. Ludvikova
University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic

The first case of post anaesthetic myelopathy in a horse is described. A two year old 530 kg Shire stallion underwent surgical removal of a granuloma in the ventral sternal region under general inhalation anaesthesia in dorsal recumbency. Total duration of the operation was 85 min. The anaesthesia was uneventful except for profuse sweating and arterial hypertension observed during the whole period. During recovery the horse was not able to stand, and flaccid paralysis of hind limbs, absence of reaction to an induced pain stimulus on the hind limbs and no patellar or anal reflex was recorded; in addition, tail tonus was weak. Panniculus reflex was absent distally from the 17th intercostal space. Head, neck and front limb movement was not affected. The horse did not respond to treatment by intravenous administration of dexamethasone, hypertonic or isotonic saline. The status deteriorated and the horse was euthanised 4 h after the end of anaesthesia. The main pathological findings were haemorrhage, oedema and malacia of L5-L6 spinal cord segments and cauda equina. Histological examination of the spinal cord revealed haemorrhage and areas of necrosis predominantly in the grey matter of L5 and L6 segments. Impairment of spinal cord perfusion due to haemodynamic changes associated with dorsal recumbency and general anaesthesia is presumed. Predisposition factors could include young age, dorsal recumbency and high weight.

Keywords: general anaesthesia; horse; myelomalacia

Published: September 30, 2014  Show citation

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Patschova M, Kabes R, Ludvikova E. Post anaesthetic myelopathy in the horse: a case report. Vet Med - Czech. 2014;59(9):447-452. doi: 10.17221/7685-VETMED.
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    References

    1. Blakemore WF, Jefferies A, White RAS, Paton IMS, Dobson H (1984): Spinal cord malacia following general anaesthesia in the horse. Veterinary Record 114, 569-570. Go to original source... Go to PubMed...
    2. Brearley JC, Jones RS, Kelly DF (1986): Spinal cord degeneration following general anaesthesia in a Shire horse. Equine Veterinary Journal 18, 222-224. Go to original source... Go to PubMed...
    3. DeGirolami U, Zivin JA (1982): Neuropathology of experimental spinal cord ischemia in the rabbit. Journal of Neuropathology and Experimental Neurology 41, 129-149. Go to original source... Go to PubMed...
    4. Dodman NH, Williams R, Court MH, Norman WM (1988): Postanesthetic hind limb adductor myopathy in five horses. Journal of the American Veterinary Medical Association 193, 83-86. Go to PubMed...
    5. Dyson S, Taylor P, Whitwell K (1988): Femoral nerve paralysis after general anaesthesia. Equine Veterinary Journal 20, 376-380. Go to original source... Go to PubMed...
    6. Grandy JL, Steffey EP, Hodgson DS, Woliner MJ (1987): Arterial hypotension and the development of postanesthetic myopathy in halothane-anesthetized horses. American Journal of Veterinary Research 48, 192-197.
    7. Griffiths IR, Burns N, Crawford AR (1978): Early vascular changes in the spinal grey matter following impact injury. Acta Neuropathologica 41, 33-39. Go to original source... Go to PubMed...
    8. Joubert KE, Duncan N, Murray SE (2005): Post-anaesthetic myelomalacia in a horse. Journal of the South African Veterinary Association 76, 36-39. Go to original source... Go to PubMed...
    9. Lam KHK, Smyth JBA, Clarke K, Platt D (1995): Acute spinal cord degeneration following general anaesthesia in a young pony. Veterinary Record 136, 329-330. Go to original source... Go to PubMed...
    10. Lerche E, Laverty S, Blais D, Sauvageau R, Cuvelliez S (1993): Hemorrhagic myelomalacia following general anesthesia in a horse. Cornell Veterinarian 83, 267-273.
    11. Lindsay WA, Robinson GM, Brunson DB, Majors LJ (1989): Induction of equine postanesthetic myositis after halothane-induced hypotension. American Journal of Veterinary Research 50, 404-410.
    12. Normann NA, Taylor AA, Crawford ES, DeBakey ME, Saleh SA (1983): Catecholamine release during and after cross clamping of descending thoracic aorta. Journal of Surgical Research 34, 97-103. Go to original source... Go to PubMed...
    13. Osterholm JL (1974): The pathophysiological response to spinal cord injury. The current status of related research. Journal of Neurosurgery 40, 5-33. Go to original source... Go to PubMed...
    14. Ragle C, Baetge C, Yiannikouris S, Dunigan C, Schneider R, Keegan R (2011): Development of equine post anaesthetic myelopathy: thirty cases (1979-2010). Equine Veterinary Education 23, 630-635. Go to original source...
    15. Raidal SR, Raidal SL, Richards RB, Cosgriff AV, Rose KJ (1997): Acute paraplegia in a Thoroughbred race-horse after general anaesthesia. Australian Veterinary Journal 75, 178-179. Go to original source... Go to PubMed...
    16. Schatzmann U, Meister V, Frankhauser R (1979): Acute haematomyelia after prolonged dorsal recumbency in the horse (in German). Schweizer Archiv fur Tierheilkunde 121, 149-155. Go to PubMed...
    17. Steffey EP, Howland D (1978): Cardiovascular effects of halothane in the horse. American Journal of Veterinary Research 39, 611-615.
    18. Steffey EP, Howland D (1980): Comparison of circulatory and respiratory effects of isoflurane and halothane anesthesia in horses. American Journal of Veterinary Research 41, 821-825.
    19. Trim CM (1997): Postanesthetic hemorrhagic myelopathy or myelomalacia. Veterinary Clinics of North America: Equine Practice 13, 73-77. Go to original source... Go to PubMed...
    20. van Loon JP, Meertens NM, van Oldruitenborgh-Oosterbaan MM, van Dijk R (2010): Post-anaesthetic myelopathy in a 3-year-old Friesian gelding. Tijdschrift voor Diergeneeskunde 135, 272-277. Go to PubMed...
    21. Yovich JV, Le Couteur RA, Stashak TS, Grandy JL, Whalen LR (1986): Postanesthetic hemorrhagic myelopathy in a horse. Journal of the American Veterinary Medical Association 188, 300-301. Go to PubMed...
    22. Zink MC (1985): Postanesthetic Poliomyelomalacia in a Horse. Canadian Veterinary Journal 26, 275-277.

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